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1. (WO2018081567) COMBINATION THERAPY FOR TREATING PULMONARY HYPERTENSION

Pub. No.:    WO/2018/081567    International Application No.:    PCT/US2017/058768
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Sat Oct 28 01:59:59 CEST 2017
IPC: A61K 31/497
A61K 9/16
Applicants: PULMOKINE, INC.
Inventors: ZISMAN, Lawrence S.
Title: COMBINATION THERAPY FOR TREATING PULMONARY HYPERTENSION
Abstract:
The present disclosure describes a method of treating pulmonary disorders, such as pulmonary arterial hypertension, using a combination of a PDGF receptor kinase inhibitor, PDEV inhibitor, and an endothelin receptor antagonist. The compounds can inhibit cell growth and proliferation and target the underlying pathology of PAH.