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1. (WO2018081442) POLYOXOMETALATE COMPLEXES AND USES IN MANAGING CANCER

Pub. No.:    WO/2018/081442    International Application No.:    PCT/US2017/058563
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Fri Oct 27 01:59:59 CEST 2017
IPC: B32B 21/02
C09K 3/14
C09D 5/08
Applicants: EMORY UNIVERSITY
Inventors: SONG, Jie
NIE, Shuming
HILL, Craig
Title: POLYOXOMETALATE COMPLEXES AND USES IN MANAGING CANCER
Abstract:
The disclosure relates polyoxometalate complexes and uses in the management, treatment, or prevention of cancer. In certain embodiments, the polyoxometalate complexes comprise polydentate oxygen bridging ligands such as those of the following formula: [POM{(OCH2)3CX}2], [M6O13{(OCH2)3CX}2], [V6O13{(OCH2)3CX}2], salts, or derivatives thereof wherein POM is a polyoxometalate, M is a metal, and X is defined herein. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising polyoxometalate complexes disclosed herein.