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1. (WO2018081440) SYSTEMS AND METHODS FOR OPTICAL SENSING OF BIOMOLECULAR TARGETS

Pub. No.:    WO/2018/081440    International Application No.:    PCT/US2017/058559
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Fri Oct 27 01:59:59 CEST 2017
IPC: G01N 15/14
Applicants: INTEGRATED NANO-TECHNOLOGIES, INC.
Inventors: CONNOLLY, Dennis, M.
MURANTE, Richard, S.
WESTCOTT, Nathaniel, E.
Title: SYSTEMS AND METHODS FOR OPTICAL SENSING OF BIOMOLECULAR TARGETS
Abstract:
A system for detection of a target molecule includes an imager, a flow cell having a functionalized surface, a light source, and a magnet. The functionalized surface is configured to bind a target molecule attracted to the functionalized surface via the magnet. The target molecule is configured to bind a nanoparticle and the light source is configured to direct a light beam toward the bound nanoparticle. Light from the nanoparticle is captured by the imager and analyzed to detect the presence of the target molecule.