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1. (WO2018081381) PYRIDAZINE DERIVATIVES, COMPOSITIONS AND METHODS FOR MODULATING CFTR

Pub. No.:    WO/2018/081381    International Application No.:    PCT/US2017/058469
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Fri Oct 27 01:59:59 CEST 2017
IPC: C07D 403/06
C07D 409/14
C07D 413/06
C07D 417/14
C07D 471/04
A61K 31/501
A61P 11/00
Applicants: PROTEOSTASIS THERAPEUTICS, INC
Inventors: PARKS, Daniel
MUNOZ, Benito
Title: PYRIDAZINE DERIVATIVES, COMPOSITIONS AND METHODS FOR MODULATING CFTR
Abstract:
The present disclosure is directed to disclosed compounds that modulate, e.g., address underlying defects in cellular processing of CFTR activity.