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1. (WO2018081314) ESTIMATION OF PERIPHERAL VASCULAR RESISTANCE USING A MINIATURE PIEZOELECTRIC SENSOR

Pub. No.:    WO/2018/081314    International Application No.:    PCT/US2017/058365
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Thu Oct 26 01:59:59 CEST 2017
IPC: A61B 5/1455
A61B 5/021
A61B 5/026
Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
Inventors: WARD, Kevin, R.
ANSARI, Sardar
WANG, Lu
NAJARIAN, Kayvan
OLDHAM, Kenn
Title: ESTIMATION OF PERIPHERAL VASCULAR RESISTANCE USING A MINIATURE PIEZOELECTRIC SENSOR
Abstract:
A wearable assembly has a pulse plethysmography (PPG) sensor and a piezoelectric pressure sensor and is attachable to a patient's finger or other area corresponding to a peripheral vascular region, and further includes a signal processor configured to monitor blood flow dependent measurements and pressure measurements over time, comparing these measurements to determine properties of the vascular region, such as vascular resistance of a blood vessel, vascular radius of the blood vessel, vascular stiffness of the vascular region, blood pressure, and/or cardiac vascular power. The signal processor may apply a hysteresis comparison of the sensor outputs, e.g., using an elliptical model, and in some examples may apply an extended Kalman filter for optimizing output of the vascular region properties.