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1. (WO2018081202) MARKERS OF CHRONIC FATIGUE SYNDROME

Pub. No.:    WO/2018/081202    International Application No.:    PCT/US2017/058189
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Thu Oct 26 01:59:59 CEST 2017
IPC: C12Q 1/68
G01N 33/50
C12N 15/113
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors: EGUCHI, Akiko
FELDSTEIN, Ariel E.
WATANABE, Yasuyoshi
FUKUDA, Sanae
KURASTUNE, Hirohiko
Title: MARKERS OF CHRONIC FATIGUE SYNDROME
Abstract:
Methods of detecting, monitoring, assessing and treating chronic fatigue syndrome (CFS) and associated diseases or conditions in a subject comprising measuring the amount of extracellular vesicles (EVs) in the bodily sample, or the expression level or activity of at least one biomarker associated with CFS expressed or detected in the EVs. The increased amount of EVs in the bodily sample and/or the increased expression or detection level of the biomarker of interest correlate with the degree or severity of CFS.