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1. (WO2018080990) ENHANCEMENT OF MSC IMMUNOMODULATORY PROPERTIES BY TREPROSTINIL

Pub. No.:    WO/2018/080990    International Application No.:    PCT/US2017/057863
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Tue Oct 24 01:59:59 CEST 2017
IPC: A61K 35/28
C12N 5/0789
A61P 9/00
A61P 9/10
A61P 11/00
Applicants: UNITED THERAPEUTICS CORPORATION
Inventors: ILAGAN, Roger Marquez
HOGAN, Sarah
CHEADLE, John B.
Title: ENHANCEMENT OF MSC IMMUNOMODULATORY PROPERTIES BY TREPROSTINIL
Abstract:
Provided are methods for treating or preventing vasculopathy comprising administering to a subject in need thereof, ac composition comprising a mesenchymal stem cell (MSC), or a part of a culture medium that has been in contact with the MSC and comprises one or more components of the MSC, or an exosome derived from the MSC. Pharmaceutical compositions suitable for such treatment is also provided.