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1. (WO2018080923) NON-INVASIVE PASSIVE INTERSTITIAL FLUID COLLECTOR
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Pub. No.: WO/2018/080923 International Application No.: PCT/US2017/057614
Publication Date: 03.05.2018 International Filing Date: 20.10.2017
IPC:
A61B 5/145 (2006.01) ,A61B 5/1477 (2006.01) ,A61B 5/1491 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1468
using chemical or electrochemical methods, e.g. by polarographic means
1477
non-invasive
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1491
Heated applicators
Applicants:
GEORGETOWN UNIVERSITY [US/US]; 37th And O Streets, N.W. Washington, DC 20057, US
Inventors:
PARANJAPE, Makarand; US
Agent:
BEY, Dawn-Marie; US
Priority Data:
62/414,44828.10.2016US
Title (EN) NON-INVASIVE PASSIVE INTERSTITIAL FLUID COLLECTOR
(FR) COLLECTEUR DE FLUIDE INTERSTITIEL PASSIF NON INVASIF
Abstract:
(EN) A microfluidic device for non-invasively and passively accessing interstitial fluid from a patient includes a substrate containing multiple vertical micro channels therethrough, wherein at a first end of each of the multiple vertical micro channels a microheater is formed for controllably ablating a portion of dry dead skin cells to access the interstitial fluid; and wherein at a second end of each of the multiple vertical micro channels is a horizontal micro channel for receiving accessed interstitial fluid from a vertical micro channel and guiding the accessed interstitial fluid to a common collection port.
(FR) La présente invention concerne un dispositif microfluidique pour accéder de façon non invasive et passive à un fluide interstitiel provenant d’un patient qui comprend un substrat contenant des microcanaux verticaux multiples à travers celui-ci, dans lequel, à une première extrémité de chacun des microcanaux verticaux multiples, un micro-dispositif de chauffage est formé pour l’ablation contrôlable d’une partie de cellules de peau mortes sèches pour accéder au fluide interstitiel ; et dans lequel, à une deuxième extrémité de chacun des microcanaux verticaux multiples est un microcanal horizontal pour recevoir un fluide interstitiel accédé provenant d’un microcanal vertical et guider le fluide interstitiel accédé vers un orifice de collecte commun.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)