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1. (WO2018080514) METHODS FOR DETECTION AND TREATMENT OF BRAIN INJURY
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Pub. No.: WO/2018/080514 International Application No.: PCT/US2016/059322
Publication Date: 03.05.2018 International Filing Date: 28.10.2016
IPC:
G01N 33/68 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants:
UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION [US/US]; 201 Gillis Building Lexington, Kentucky 40506-0033, US
Inventors:
LOVELL, Mark A.; US
LYNN, Bert C.; US
BRADLEY-WHITMAN, Melissa A.; US
Agent:
VETTER, Michael L.; US
AUGST, Alexander D.; US
BUTEAU, Kristen C.; US
CAHILL, John J.; US
HAULBROOK, William R.; US
JARRELL, Brenda Herschbach; US
LI, Xiaodong; US
LYON, Charles E.; US
MEDINA, Rolando; US
MONROE, Margo R.; US
NGUYEN, Suzanne P.; US
NIHAN, Danielle M.; US
PACE, Nicholas J.; US
PELLIGRINO, Jeffrey S.; US
PYSHER, Paul A.; US
REARICK, John P.; US
REESE, Brian E.; US
ROHLFS, Elizabeth M.; US
SAHR, Robert N.; US
SCHONEWALD, Stephanie L.; US
SHAIKH, Nishat A.; US
SHINALL, Michael A.; US
SMITH, Maria C.; US
SUH, Su Kyung; US
VRABLIK, Tracy L.; US
WANG, Gang; US
Priority Data:
Title (EN) METHODS FOR DETECTION AND TREATMENT OF BRAIN INJURY
(FR) MÉTHODES DE DÉTECTION ET DE TRAITEMENT D’UNE LÉSION CÉRÉBRALE
Abstract:
(EN) The present disclosure provides devices, in particular lateral flow devices, compositions, and methods, that utilize ordered application of antibodies selective for different portions of VTLIP-1 to process and/or analyze biological samples, for example from subjects who have suffered traumatic brain injury.
(FR) La présente invention concerne des dispositifs, en particulier des dispositifs à écoulement latéral, des compositions et des méthodes, qui utilisent l'application ordonnée d'anticorps sélectifs pour différentes parties de VTLIP-1 pour traiter et/ou analyser des échantillons biologiques, par exemple à partir de sujets qui ont souffert d'une lésion cérébrale traumatique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)