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1. (WO2018080308) SURFACE TOPOGRAPHIES FOR STIMULATING ENDOTHELIALIZATION
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/080308    International Application No.:    PCT/NL2017/050701
Publication Date: 03.05.2018 International Filing Date: 30.10.2017
IPC:
A61F 2/28 (2006.01), A61F 2/30 (2006.01), A61C 8/00 (2006.01)
Applicants: MATERIOMICS B.V. [NL/NL]; Oxfordlaan 70 6229 EV Maastricht (NL)
Inventors: PAPENBURG, Berendien Jacoba; (NL).
DE BOER, Jan; (NL).
HULSHOF, Godefridus Franciscus Bernardus; (NL)
Agent: JANSEN, C.M.; V.O. Carnegieplein 5 2517 KJ Den Haag (NL)
Priority Data:
2017684 28.10.2016 NL
PCT/NL2017/050092 16.02.2017 NL
Title (EN) SURFACE TOPOGRAPHIES FOR STIMULATING ENDOTHELIALIZATION
(FR) TOPOGRAPHIES DE SURFACE POUR STIMULER L'ENDOTHÉLIALISATION
Abstract: front page image
(EN)The invention pertains to surface topographies which can be used to modulate the morphology, proliferation, biochemical functioning, differentiation, attachment, migration, signaling, and/or cell death of an endothelial cell population by physical stimulation. Such topographies can be applied in vitro and in vivo to modulate cell behavior. Specific examples include vascular or lymphatic implants provided with a topography of the invention which increase endothelialization.
(FR)L'invention concerne des topographies de surface qui peuvent être utilisées de manière à moduler la morphologie, la prolifération, le fonctionnement biochimique, la différenciation, la fixation, la migration, la signalisation et/ou la mort cellulaire d'une population de cellules endothéliales par stimulation physique. Ces topographies peuvent être appliquées in vitro et in vivo de manière à moduler le comportement cellulaire. Des exemples spécifiques comprennent des implants vasculaires ou lymphatiques dotés d'une topographie de l'invention qui augmentent l'endothélialisation.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)