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1. (WO2018080252) IMMUNE RESPONSE REGULATORY SUBSTANCE AND VACCINE COMPOSITION CONTAINING SAME

Pub. No.:    WO/2018/080252    International Application No.:    PCT/KR2017/012050
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Tue Oct 31 00:59:59 CET 2017
IPC: A61K 39/12
A61K 39/295
A61K 39/39
A61K 39/002
A61K 39/00
Applicants: EYEGENE INC.
아이진 주식회사
Inventors: CHO, Yang Je
조양제
KIM, Kwangsung
김광성
LEE, Na Gyong
이나경
PARK, Shin Ae
박신애
Title: IMMUNE RESPONSE REGULATORY SUBSTANCE AND VACCINE COMPOSITION CONTAINING SAME
Abstract:
The present invention relates to an immune response regulatory substance having a novel structure, and an immunologic adjuvant composition containing the same and, more specifically, to an immune response regulatory substance, which is a lipopolysaccharide (LPS) analog having reduced toxicity, and a use thereof. The immune response regulatory substance of the present invention exhibits immune enhancement effects by having excellent innate immunity and ability to induce an adaptive immune response to a specific pathogen, and is very safe by having lox toxicity. In addition, a vaccine containing the immune response regulatory substance of the present invention contains both an immune response regulatory substance and an alum, thereby improving immune enhancement effects compared with when using only the immune response regulatory substance.