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1. (WO2018080166) 3,4,5-TRIMETHOXYCINNAMIC ACID ESTER DERIVATIVE, METHOD FOR PREPARING SAME, AND SKIN WHITENING COMPOSITION COMPRISING SAME
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Pub. No.: WO/2018/080166 International Application No.: PCT/KR2017/011848
Publication Date: 03.05.2018 International Filing Date: 25.10.2017
IPC:
C07C 69/618 (2006.01) ,A61K 8/36 (2006.01) ,A61Q 19/02 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
69
Esters of carboxylic acids; Esters of carbonic or haloformic acids
612
Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
618
having unsaturation outside the six-membered aromatic ring
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
33
containing oxygen
36
Carboxylic acids; Salts or anhydrides thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q
SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19
Preparations for care of the skin
02
for chemically bleaching or whitening the skin
Applicants:
(주)아모레퍼시픽 AMOREPACIFIC CORPORATION [KR/KR]; 서울시 용산구 한강로 100 100, Hangang-daero Yongsan-gu Seoul 04386, KR
Inventors:
노호식 RHO, Ho Sik; KR
김용진 KIM, Yong Jin; KR
박녹현 PARK, Nok Hyun; KR
이존환 LEE, John Hwan; KR
이창석 LEE, Chang Seok; KR
Agent:
김성호 KIM, Sung Ho; KR
박형달 PARK, Hyung-Dal; KR
김병필 KIM, Byeong Pil; KR
Priority Data:
10-2016-014042526.10.2016KR
Title (EN) 3,4,5-TRIMETHOXYCINNAMIC ACID ESTER DERIVATIVE, METHOD FOR PREPARING SAME, AND SKIN WHITENING COMPOSITION COMPRISING SAME
(FR) DÉRIVÉ D'ESTER D'ACIDE 3,4,5-TRIMÉTHOXYCINNAMIQUE, SON PROCÉDÉ DE PRÉPARATION ET COMPOSITION DE BLANCHIMENT DE LA PEAU LE COMPRENANT
(KO) 3,4,5-트리메톡시 신남산 에스테르 유도체와 그 제조방법 및 이를 포함하는 피부 미백용 조성물
Abstract:
(EN) The present invention relates to a novel 3,4,5-trimethoxycinnamic acid ester derivative, a method for preparing the same, and a skin whitening cosmetic composition comprising the same. The compound shows a skin whitening effect by acting on tyrosinase, which is a melanin producing enzyme, to suppress the production of melanin, and exhibits an improved skin whitening effect compared with kojic acid that has been previously known as an existing skin whitening agent, and thus the composition of the present invention can be variously applied to all kinds of cosmetic products or externally-applicable dermal preparations for skin whitening.
(FR) La présente invention concerne un nouveau dérivé d'ester d'acide 3,4,5-triméthoxycinnamique, son procédé de préparation, et une composition cosmétique de blanchiment le comprenant. Le composé présente un effet de blanchiment de la peau en agissant sur la tyrosinase, qui est une enzyme produisant de la mélanine, pour supprimer la production de mélanine, et présente un effet de blanchiment de la peau amélioré par rapport à l'acide kojique qui a été précédemment connu en tant qu'agent de blanchiment de la peau existant, la composition de la présente invention pouvant ainsi être appliquée de diverses manières à tous types de produits cosmétiques ou de préparations dermiques à application externe pour le blanchiment de la peau.
(KO) 본 발명은 신규한 3,4,5-트리메톡시 신남산 에스테르 유도체, 이의 제조방법 및 이를 포함하는 미백용 화장료 조성물에 관한 것이다. 상기 화합물은 멜라닌을 생성하는 효소인 티로시나제에 작용하여 멜라닌의 생산을 억제함으로써 피부 미백효과를 나타내며, 기존에 피부 미백제로 알려진 코지산에 비하여 향상된 피부 미백 효과를 나타내, 피부 미백을 위한 각종 화장품이나 피부 외용제 등에 다양하게 적용될 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)