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1. (WO2018080072) NOVEL MACROLIDE-BASED COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MALARIA AND CONTAINING SAME AS ACTIVE INGREDIENT
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Pub. No.: WO/2018/080072 International Application No.: PCT/KR2017/011396
Publication Date: 03.05.2018 International Filing Date: 16.10.2017
IPC:
C07H 17/08 (2006.01) ,A61K 31/70 (2006.01) ,C12N 1/20 (2006.01)
Applicants: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY[KR/KR]; 125, Gwahak-ro Yuseong-gu Daejeon 34141, KR
Inventors: AHN, Jong Seog; KR
JANG, Jae-Hyuk; KR
KO, Sung-Kyun; KR
RYOO, In Ja; KR
SON, Sang Keun; KR
KIM, Bo Yeon; KR
SOUNG, Nak Kyun; KR
LEE, Kyung Ho; KR
HONG, Young-Soo; KR
Agent: AHN, So Young; KR
Priority Data:
10-2016-014089827.10.2016KR
10-2017-012850902.10.2017KR
Title (EN) NOVEL MACROLIDE-BASED COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MALARIA AND CONTAINING SAME AS ACTIVE INGREDIENT
(FR) NOUVEAU COMPOSÉ À BASE DE MACROLIDE, SON PROCÉDÉ DE PRODUCTION, ET COMPOSITION PHARMACEUTIQUE DESTINÉE À PRÉVENIR OU À TRAITER LE PALUDISME ET LE CONTENANT À TITRE DE PRINCIPE ACTIF
(KO) 신규한 매크로라이드계 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 말라리아의 예방 또는 치료용 약학적 조성물
Abstract: front page image
(EN) The present invention relates to a novel macrolide-based compound, a method for producing the same, and a pharmaceutical composition, which is for preventing or treating malaria and contains the novel macrolide-based compound as an active ingredient. The macrolide-based compound represented by chemical formula 1 according to the present invention effectively exhibits an antiprotozoal activity against Plasmodium sp. protozoan, and thus can be usefully used to prevent or treat malaria.
(FR) La présente invention concerne un nouveau composé à base de macrolide, son procédé de production, et une composition pharmaceutique, qui est destinée à prévenir ou à traiter le paludisme et le contenant à titre de principe actif. Le composé à base de macrolide représenté par la formule chimique 1 selon la présente invention présente une activité antiprotozoaire efficace contre le protozoaire Plasmodium sp., et peut par conséquent être utilisé de manière utile pour prévenir ou traiter le paludisme.
(KO) 본 발명은 신규한 매크로라이드계 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 말라리아의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명에 따른 화학식 1로 표시되는 매크로라이드계 화합물은 플라스모듐 속(Plasmodium sp.) 원충에 대하여 항원충 활성을 효과적으로 나타내어 말라리아의 예방 또는 치료에 유용하게 사용될 수 있는 효과가 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)