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1. (WO2018080054) COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING ARTHRITIS, CONTAINING EXTRACT OF MOLLUGO PENTAPHYLLA AS ACTIVE INGREDIENT

Pub. No.:    WO/2018/080054    International Application No.:    PCT/KR2017/011224
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Fri Oct 13 01:59:59 CEST 2017
IPC: A23L 33/105
A61K 36/36
Applicants: KOREA INSTITUTE OF ORIENTAL MEDICINE
한국 한의학 연구원
Inventors: KIM, Dong Seon
김동선
LEE, Yun Mi
이윤미
SON, Eun Jung
손은정
KIM, Ohn Soon
김온순
LEE, Young-Sil
이영실
Title: COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING ARTHRITIS, CONTAINING EXTRACT OF MOLLUGO PENTAPHYLLA AS ACTIVE INGREDIENT
Abstract:
The present invention relates to a composition for preventing, alleviating or treating arthritis, containing an extract of Mollugo pentaphylla as an active ingredient. More specifically, the Mollugo pentaphylla extract of the present invention is not cytotoxic, has an effect of inhibiting the generation of NO, induced by inflammation, and the increase in TNFα, PGE2, and IL-6, reduces the IL-1β amount increased because of gouty arthritis, relieves pain caused by osteoarthritis, and reduces the amount of inflammatory cytokines, thereby being usable in the prevention, alleviation or treatment of arthritis.