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1. (WO2018080054) COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING ARTHRITIS, CONTAINING EXTRACT OF MOLLUGO PENTAPHYLLA AS ACTIVE INGREDIENT
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/080054    International Application No.:    PCT/KR2017/011224
Publication Date: 03.05.2018 International Filing Date: 12.10.2017
IPC:
A23L 33/105 (2016.01), A61K 36/36 (2006.01)
Applicants: KOREA INSTITUTE OF ORIENTAL MEDICINE [KR/KR]; 1672, Yuseong-daero Yuseong-gu Daejeon 34054 (KR)
Inventors: KIM, Dong Seon; (KR).
LEE, Yun Mi; (KR).
SON, Eun Jung; (KR).
KIM, Ohn Soon; (KR).
LEE, Young-Sil; (KR)
Agent: CHOI, Kyu Whan; (KR)
Priority Data:
10-2016-0139993 26.10.2016 KR
Title (EN) COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING ARTHRITIS, CONTAINING EXTRACT OF MOLLUGO PENTAPHYLLA AS ACTIVE INGREDIENT
(FR) COMPOSITION DESTINÉE À LA PRÉVENTION, AU SOULAGEMENT OU AU TRAITEMENT DE L'ARTHRITE, COMPRENANT UN EXTRAIT DE MOLLUGO PENTAPHYLLA EN TANT QUE PRINCIPE ACTIF
(KO) 석류풀 추출물을 유효성분으로 함유하는 관절염의 예방, 개선 또는 치료용 조성물
Abstract: front page image
(EN)The present invention relates to a composition for preventing, alleviating or treating arthritis, containing an extract of Mollugo pentaphylla as an active ingredient. More specifically, the Mollugo pentaphylla extract of the present invention is not cytotoxic, has an effect of inhibiting the generation of NO, induced by inflammation, and the increase in TNFα, PGE2, and IL-6, reduces the IL-1β amount increased because of gouty arthritis, relieves pain caused by osteoarthritis, and reduces the amount of inflammatory cytokines, thereby being usable in the prevention, alleviation or treatment of arthritis.
(FR)La présente invention concerne une composition destinée à la prévention, au soulagement ou au traitement de l’arthrite, comprenant un extrait de Mollugo pentaphylla en tant que principe actif. Plus précisément, l'extrait de Mollugo pentaphylla de la présente invention n'est pas cytotoxique, a pour effet d'inhiber la génération de NO, induite par l'inflammation, et l'augmentation du TNFα, de la PGE2, et d’IL-6, réduit la quantité d'IL-1β augmentée en raison de l'arthrite goutteuse, soulage de la douleur provoquée par l'arthrose, et réduit la quantité de cytokines inflammatoires, permettant ainsi une utilisation dans la prévention, le soulagement ou le traitement de l'arthrite.
(KO)본 발명은 석류풀 추출물을 유효성분으로 함유하는 관절염의 예방, 개선 또는 치료용 조성물에 관한 것으로, 상세하게는 본 발명의 석류풀 추출물은 세포 독성이 없으며, 염증에 의해 유도되는 NO의 생성, TNFα, PGE2 및 IL-6의 증가를 억제하는 효과가 있고, 통풍성 관절염에 의해 증가된 IL-1β의 함량을 감소시킬 뿐만 아니라, 골관절염에 의한 통증을 완화시키며, 염증성 사이토카인의 함량을 감소시킴으로써, 관절염의 예방, 개선 또는 치료에 유용하게 사용할 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)