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1. (WO2018079988) COMPOUND USEFUL AS TRAP1 INHIBITOR, AND ANTICANCER COMPOSITION CONTAINING SAME
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/079988 International Application No.: PCT/KR2017/007907
Publication Date: 03.05.2018 International Filing Date: 21.07.2017
IPC:
A61K 31/519 (2006.01) ,A61K 31/36 (2006.01) ,C07D 487/04 (2006.01) ,C07D 317/46 (2006.01)
Applicants: UNIST(ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY)[KR/KR]; 50, UNIST-gil Eonyang-eup Ulju-gun Ulsan 44919, KR
Inventors: KANG, Byoung Heon; KR
PARK, Hye Kyung; KR
LEE, Changwook; KR
KANG, Soosung; KR
LEE, Ji Hoon; KR
HONG, Ki-Bum; KR
KIM, Darong; KR
LEE, Won Seok; KR
KO, Eunhwa; KR
LEE, Sang Kwang; KR
KIM, Seong Heon; KR
LEE, Geum Woo; KR
Agent: YOU ME PATENT AND LAW FIRM; 115 Teheran-ro, Gangnam-gu, Seoul 06134, KR
Priority Data:
10-2016-014026026.10.2016KR
Title (EN) COMPOUND USEFUL AS TRAP1 INHIBITOR, AND ANTICANCER COMPOSITION CONTAINING SAME
(FR) COMPOSÉ UTILE EN TANT QU'INHIBITEUR DE TRAP1, ET COMPOSITION ANTICANCÉREUSE LE CONTENANT
(KO) TRAP1 저해제로서 유용한 화합물 및 이를 포함하는 항암용 조성물
Abstract: front page image
(EN) The present invention relates to a compound simultaneously inhibiting a heat shock protein Hsp90 and a Hsp90 homologous protein such as TRAP1 and, more specifically, to: a compound having a structure of the following chemical formula I, and being useful as an inhibitor of Hsp90 and a homologous protein thereof; and an anticancer composition containing the same.
(FR) La présente invention concerne un composé inhibant simultanément une protéine de choc thermique Hsp90 et une protéine homologue Hsp90 telle que TRAP1 et, plus spécifiquement: un composé qui a une structure de formule chimique I suivante, et qui est utile en tant qu'inhibiteur de Hsp90 et d'une protéine homologue de celle-ci; et une composition anticancéreuse contenant ledit composé.
(KO) 본 발명은 열 충격 단백질 (heat shock protein) Hsp90및 TRAP1과 같은 Hsp90 상동단백질을 동시에 저해하는 화합물에 관한 것으로서, 보다 상세하게는 하기 화학식 I의 구조를 갖는 Hsp90 및 이의 상동단백질 저해제로서 유용한 화합물 및 이를 포함하는 항암용 조성물에 관한 것이다:
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)