Search International and National Patent Collections

1. (WO2018079951) NEW RESORCINARENE-BASED AMPHIPATHIC COMPOUND AND USE THEREOF

Pub. No.:    WO/2018/079951    International Application No.:    PCT/KR2017/002871
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Sat Mar 18 00:59:59 CET 2017
IPC: C07H 15/18
C07K 1/113
C07K 1/14
C07K 1/30
C07K 14/705
G01N 33/68
B82Y 5/00
Applicants: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS
한양대학교 에리카산학협력단
Inventors: CHAE, Pil Seok
채필석
HUSSAIN, Hazrat
후세인하즈랏
Title: NEW RESORCINARENE-BASED AMPHIPATHIC COMPOUND AND USE THEREOF
Abstract:
The present invention relates to a newly developed resorcinarene-based amphipathic compound, a method for producing the same, and a method for extracting, solubilizing, stabilizing, crystallizing, or analyzing a membrane protein by using the same. In addition, compared to a conventional compound, the compound can efficiently extract from a cell membrane, membrane proteins having a greater variety of structures and characteristics, and can stably store such membrane proteins for a long time in an aqueous solution. Therefore, the compound can be used to analyze the functions and structures of such membrane proteins. Analysis of the structures and functions of membrane proteins, being closely related to the development of new drugs, is one of the fields of greatest interest in biology and chemistry today.