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|1. (WO2018079951) NEW RESORCINARENE-BASED AMPHIPATHIC COMPOUND AND USE THEREOF|
|Applicants:||INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS
|Inventors:||CHAE, Pil Seok
|Title:||NEW RESORCINARENE-BASED AMPHIPATHIC COMPOUND AND USE THEREOF|
The present invention relates to a newly developed resorcinarene-based amphipathic compound, a method for producing the same, and a method for extracting, solubilizing, stabilizing, crystallizing, or analyzing a membrane protein by using the same. In addition, compared to a conventional compound, the compound can efficiently extract from a cell membrane, membrane proteins having a greater variety of structures and characteristics, and can stably store such membrane proteins for a long time in an aqueous solution. Therefore, the compound can be used to analyze the functions and structures of such membrane proteins. Analysis of the structures and functions of membrane proteins, being closely related to the development of new drugs, is one of the fields of greatest interest in biology and chemistry today.