Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018079899) METHOD FOR MANUFACTURING DRY/WET WOUND DRESSING, AND WOUND DRESSING MANUFACTURED THEREBY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/079899 International Application No.: PCT/KR2016/012479
Publication Date: 03.05.2018 International Filing Date: 01.11.2016
IPC:
A61F 13/00 (2006.01) ,A61L 15/28 (2006.01) ,A61L 15/18 (2006.01) ,A61L 15/32 (2006.01) ,A61F 13/02 (2006.01)
[IPC code unknown for A61F 13][IPC code unknown for A61L 15/28][IPC code unknown for A61L 15/18][IPC code unknown for A61L 15/32][IPC code unknown for A61F 13/02]
Applicants:
주식회사 유엔헬스케어 UNHEALTHCARE CO., LTD. [KR/KR]; 충청북도 옥천군 옥천읍 의료단지길 79, 201호 (옥천의료기기보육센터) (Okcheon Medical Instrument Nursery) 201ho 79, Uiryodanji-gil Okcheon-eup, Okcheon-gun Chungcheongbuk-do 29055, KR
Inventors:
김태준 KIM, Tae Jun; KR
Agent:
김정수 KIM, Jung Su; KR
Priority Data:
10-2016-014092627.10.2016KR
10-2016-014093127.10.2016KR
Title (EN) METHOD FOR MANUFACTURING DRY/WET WOUND DRESSING, AND WOUND DRESSING MANUFACTURED THEREBY
(FR) PROCÉDÉ DE FABRICATION D'UN PANSEMENT SEC/HUMIDE, ET PANSEMENT AINSI FABRIQUÉ
(KO) 건습식형 창상피복재의 제조방법 및 이에 의해 제조된 창상피복재
Abstract:
(EN) The present invention provides a method for manufacturing a wound dressing, comprising the steps of: (a) coating a first mixture solution containing an organic acid and 0.01-3 wt% of chitosan so as to form a blood coagulation assisting layer on the upper surface of a fabric layer included in a gauze part; (b) forming a blood coagulation promotion layer by coating a second mixture solution, containing 0.1-20 wt% of kaolin, on the upper surface of the blood coagulation assisting layer in step (a), thereby manufacturing the gauze part comprising the fabric layer having the blood coagulation assisting layer and the blood coagulation promotion layer, which are sequentially stacked thereon; (c) coating an adhesive on one surface so as to manufacture a support part comprising an adhesive layer; and (d) attaching the gauze part, which is manufactured in step (b), to the upper surface of the adhesive layer of the support part, which is manufactured in step (c). According to the present invention, the method for manufacturing a wound dressing forms a blood coagulation assisting layer by coating a first mixture solution containing an organic acid and chitosan on a fabric layer, and forms a blood coagulation promotion layer by coating a second solution, containing kaolin, on the upper surface of the blood coagulation assisting layer, and thus kaolin becomes negatively charged through the pH of the organic acid contained in the blood coagulation assisting layer, and positively charged chitosan and kaolin are bound so as to have sufficient bonding force through an ionic bond, thereby effectively preventing the separation of kaolin from a fabric, and thus a wound dressing exhibiting an excellent hemostatic effect can be manufactured.
(FR) La présente invention concerne un procédé de fabrication d'un pansement, comprenant les étapes consistant : (a) à revêtir une première solution de mélange contenant un acide organique et 0,01 à 3 % en poids de chitosane de manière à former une couche d'aide à la coagulation sanguine sur la surface supérieure d'une couche de tissu comprise dans une partie gaze; (b) à former une couche favorisant la coagulation sanguine par revêtement d'une seconde solution de mélange, contenant de 0,1 à 20 % en poids de kaolin, sur la surface supérieure de la couche d'aide à la coagulation sanguine de l'étape (a), ce qui permet de fabriquer la partie gaze comprenant la couche de tissu ayant la couche d'aide à la coagulation sanguine et la couche favorisant la coagulation sanguine, qui sont séquentiellement empilées dessus; (c) à revêtir un adhésif sur une surface de façon à fabriquer une partie support comprenant une couche adhésive; et (d) à fixer la partie gaze, qui est fabriquée à l'étape (b), sur la surface supérieure de la couche adhésive de la partie support, qui est fabriquée à l'étape (c). Selon la présente invention, le procédé de fabrication d'un pansement forme une couche d'aide à la coagulation sanguine par revêtement d'une première solution de mélange contenant un acide organique et du chitosane sur une couche de tissu, et forme une couche favorisant la coagulation sanguine par revêtement d'une seconde solution, contenant du kaolin, sur la surface supérieure de la couche d'aide à la coagulation sanguine, et ainsi le kaolin devient chargé négativement par l'intermédiaire du pH de l'acide organique contenu dans la couche d'aide à la coagulation sanguine, et le chitosane et le kaolin chargés positivement sont liés de manière à avoir une force de liaison suffisante par l'intermédiaire d'une liaison ionique, ce qui permet d'empêcher efficacement la séparation du kaolin d'un tissu, ainsi un pansement présentant un excellent effet hémostatique peut être fabriqué.
(KO) 본 발명은 (a) 유기산 및 0.01 내지 3 중량%로 키토산을 포함하는 제1 혼합용액을 도포하여 거즈부에 포함된 직물층의 상면에 혈액응고 보조층을 형성시키는 단계; (b) 상기 단계 (a)에서 상기 혈액응고 보조층의 상면에 0.1 내지 20 중량%로 카올린을 포함하는 제2 혼합용액을 도포하여 혈액응고 촉진층을 형성시켜, 혈액응고 보조층 및 혈액응고 촉진층이 순차적으로 적층된 직물층을 포함하는 거즈부를 제조하는 단계; (c) 일면에 점착제를 도포하여 점착층을 포함하는 지지부를 제조하는 단계; 및 (d) 상기 단계 (b)에서 제조한 거즈부를 상기 단계 (c)에서 제조한 지지부의 점착층 상면에 부착하는 단계를 포함하는 창상피복재의 제조방법을 제공한다. 본 발명에 따른 창상피복재의 제조방법은 직물층에 유기산 및 키토산을 포함하는 제1 혼합용액을 도포하여 혈액응고 보조층을 형성시키고, 혈액응고 보조층의 상면에 카올린을 포함하는 제2 용액을 도포하여 혈액응고 촉진층을 형성시켜, 혈액응고 보조층에 포함된 유기산의 pH로 인해 카올린이 음전하를 띄고, 양전하를 띄는 키토산과 카올린이 이온결합을 통해 충분한 결합력을 갖도록 결합되어 직물에서 카올린의 이탈이 효과적으로 방지되어 우수한 지혈 효과를 나타내는 창상피복재를 제조할 수 있다.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)