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1. (WO2018078418) METHOD AND SYSTEM FOR INDICATING MUSCULAR DISORDERS

Pub. No.:    WO/2018/078418    International Application No.:    PCT/IB2016/056424
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Thu Oct 27 01:59:59 CEST 2016
IPC: G01N 21/00
Applicants: INDIAN INSTITUTE OF SCIENCE
Inventors: KADBUR PRABHAKAR RAO, Venkatesh
JAYARAM, Mohan
NONGTHOMBA, Upendra
PRATAP, Rudra
Title: METHOD AND SYSTEM FOR INDICATING MUSCULAR DISORDERS
Abstract:
The present invention relates to a method for an in vitro indication of muscular disorders, based on vibration signature of muscle fibers and cells, where suspended control and blind muscle fibers or cells are subjected to vibrations to measure the frequency responses and the frequency responses are compared to indicate a muscular disorder. The present invention also relates to a system for indication of muscular disorders comprising a vibrating base member with holders, to suspend a vibrating control muscle and blind muscle fibers or cells between the holders. A non-contact probe with a beam emitter and a receiver disposed to direct incident beams to the base member and the control and blind muscle fibers or cells and to receive the backscatter of the incident beams. A vibrometer is connected to the non-contact probe to demodulate the change in frequency and phase of the backscattered incident beams and a processing member to capture and compare the frequency response of control and blind members or cells to indicate a muscular disorder or a disease.