Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018078383) PHARMACEUTICAL COMPOSITION COMPRISING AMORPHOUS SELEXIPAG
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/078383 International Application No.: PCT/GB2017/053243
Publication Date: 03.05.2018 International Filing Date: 27.10.2017
IPC:
C07D 241/20 (2006.01) ,A61K 31/4965 (2006.01) ,A61K 9/10 (2006.01) ,A61P 9/12 (2006.01) ,A61P 11/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
241
Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
02
not condensed with other rings
10
having three double bonds between ring members or between ring members and non-ring members
14
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
20
Nitrogen atoms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
4965
Non-condensed pyrazines
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
12
Antihypertensives
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
Applicants:
CIPLA LIMITED [IN/IN]; Cipla House Peninsula Business Park Ganpatrao Kadam Marg, Lower Parel Mumbai 400 013, IN
KING, Lawrence [GB/GB]; GB (MW)
Inventors:
RAO, Dharmaraj Ramachandra; IN
MALHOTRA, Geena; IN
PATHI, Srinivas Laxminarayan; IN
PUPPALA, Ravikumar; IN
RANKIREDDI, Anand Ramesh; IN
KOMMULA, Narayanaswami; IN
GANGRADE, Manish Gopaldas; IN
Agent:
A.A. THORNTON & CO.; 10 Old Bailey London EC4M 7NG, GB
Priority Data:
20162103694927.10.2016IN
20162103862711.11.2016IN
Title (EN) PHARMACEUTICAL COMPOSITION COMPRISING AMORPHOUS SELEXIPAG
(FR) COMPOSITION PHARMACEUTIQUE COMPRENANT DU SELEXIPAG AMORPHE
Abstract:
(EN) The present invention is directed to solid state forms of selexipag (Formula (I)), including an amorphous form of selexipag and a selexipag-containing premix, to methods for their preparation, to pharmaceutical compositions comprising them and to their use in medicine, particularly for the treatment of pulmonary arterial hypertension. (Formula (I))
(FR) La présente invention concerne des formes à l'état solide de selexipag (formule (I)), comprenant une forme amorphe du selexipag et un pré-mélange contenant du selexipag, des méthodes pour leur préparation, des compositions pharmaceutiques les comprenant et leur utilisation en médecine, en particulier pour le traitement de l'hypertension artérielle pulmonaire. (Formule (I))
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)