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1. (WO2018078369) VIRAL PACKAGING SIGNALS

Pub. No.:    WO/2018/078369    International Application No.:    PCT/GB2017/053225
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Fri Oct 27 01:59:59 CEST 2017
IPC: C12N 15/115
Applicants: THE UNIVERSITY OF YORK
UNIVERSITY OF LEEDS
UNIVERSITY OF HELSINKI
Inventors: TWAROCK, Reidun
DYKEMAN, Eric Charles
STOCKLEY, Peter
WHITE, Simon
BUTCHER, Sarah
SHAKEEL, Shabih
Title: VIRAL PACKAGING SIGNALS
Abstract:
We disclose packaging signals of RNA viruses, in particular viruses of the family Picornaviridae or Retroviridae, pharmaceutical compositions comprising anti-viral agents and screening methods enabling the identification of anti-viral agents based on the amino acid binding co-ordinates of capsid proteins to which said packaging signals interact.