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Pub. No.:    WO/2018/078369    International Application No.:    PCT/GB2017/053225
Publication Date: 03.05.2018 International Filing Date: 26.10.2017
C12N 15/115 (2010.01)
Applicants: THE UNIVERSITY OF YORK [GB/GB]; Heslington York Yorkshire YO10 5DD (GB).
UNIVERSITY OF LEEDS [GB/GB]; Woodhouse Lane Horsforth Leeds, Yorkshire LS2 9JT (GB).
UNIVERSITY OF HELSINKI [FI/FI]; Yliopistokatu 4 POB 33 00014 Helsinki (FI)
Inventors: TWAROCK, Reidun; (GB).
DYKEMAN, Eric Charles; (GB).
STOCKLEY, Peter; (GB).
WHITE, Simon; (US).
BUTCHER, Sarah; (FI).
SHAKEEL, Shabih; (FI)
Agent: SYMBIOSIS IP LIMITED; NAFIC Sand Hutton York, Yorkshire YO41 1LZ (GB)
Priority Data:
1618094.5 26.10.2016 GB
Abstract: front page image
(EN)We disclose packaging signals of RNA viruses, in particular viruses of the family Picornaviridae or Retroviridae, pharmaceutical compositions comprising anti-viral agents and screening methods enabling the identification of anti-viral agents based on the amino acid binding co-ordinates of capsid proteins to which said packaging signals interact.
(FR)Nous divulguons des signaux d'encapsidation de virus à ARN, en particulier des virus de la famille Picornaviridae ou Retroviridae, des compositions pharmaceutiques comprenant des agents antiviraux et des méthodes de criblage permettant l'identification d'agents antiviraux en fonction des coordonnées de liaison à l'acide aminé, de protéines de capside par rapport auxquelles lesdits signaux d'encapsidation interagissent.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)