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1. (WO2018078363) PROCESS FOR THE PREPARATION OF (3S,4S)-TETRAHYDROFURAN-3-YL 4-ISOPROPYL-6,7-DIHYDRO-3H-IMIDAZO[4,5-C]PYRIDINE-5(4H)-CARBOXYLATE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/078363    International Application No.:    PCT/GB2017/053218
Publication Date: 03.05.2018 International Filing Date: 25.10.2017
IPC:
C07D 471/04 (2006.01), C07C 59/50 (2006.01), C07C 309/04 (2006.01)
Applicants: PROXIMAGEN LIMITED [GB/GB]; Minerva Building 250 Babraham Research Campus Cambridge Cambridgeshire CB22 3AT (GB)
Inventors: HORGAN, Anne; (GB).
HAGLUND, Olof; (GB).
PATIENT, Lee; (GB).
SAVORY, Edward; (GB).
HIGGINBOTTOM, Michael; (GB).
ASHWOOD, Michael; (GB)
Agent: GILL JENNINGS & EVERY LLP; The Broadgate Tower 20 Primrose Street London EC2A 2ES (GB)
Priority Data:
1618029.1 25.10.2016 GB
Title (EN) PROCESS FOR THE PREPARATION OF (3S,4S)-TETRAHYDROFURAN-3-YL 4-ISOPROPYL-6,7-DIHYDRO-3H-IMIDAZO[4,5-C]PYRIDINE-5(4H)-CARBOXYLATE
(FR) PROCÉDÉ DE PRÉPARATION DE (3S,4S)-TÉTRAHYDROFURAN-3-YL 4-ISOPROPYL -6,7-DIHYDRO -3 H-IMIDAZO [4,5-C] PYRIDINE -5 (4H)-CARBOXYLATE
Abstract: front page image
(EN)The invention relates to an improved process for the synthesis of (3S,4S)-tetrahydrofuran-3-yl 4-isopropyl-6,7-dihydro-3H-imidazo[4,5-c]pyridine-5(4H)-carboxylate, and pharmaceutically acceptable salts thereof, such as the methanesulphonic acid salt.
(FR)L'invention concerne un procédé amélioré de synthèse de (3S,4S)-tétrahydrofuran-3-yl 4-isopropyl -6,7-dihydro -3 H-imidazo [4,5-c] pyridine -5 (4H)-carboxylate, et des sels pharmaceutiquement acceptables de celui-ci, tels que le sel d'acide méthanesulfonique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)