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1. (WO2018078038) COMBINATION TREATMENTS COMPRISING IMIDAZOPYRAZINONES FOR THE TREATMENT OF PSYCHIATRIC AND/OR COGNITIVE DISORDERS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/078038 International Application No.: PCT/EP2017/077497
Publication Date: 03.05.2018 International Filing Date: 26.10.2017
IPC:
A61K 31/4985 (2006.01) ,A61K 31/5377 (2006.01) ,A61K 31/55 (2006.01) ,A61K 45/06 (2006.01) ,A61P 25/18 (2006.01) ,A61P 25/22 (2006.01) ,A61P 25/24 (2006.01) ,A61P 25/28 (2006.01)
Applicants: H. LUNDBECK A/S[DK/DK]; Ottiliavej 9 2500 Valby, DK
Inventors: KEHLER, Jan; DK
RASMUSSEN, Lars, Kyhn; DK
LANGGÅRD, Morten; DK
JESSING, Mikkel; DK
VITAL, Paulo, Jorge, Vieira; DK
JUHL, Karsten; DK
Priority Data:
PA20160065928.10.2016DK
Title (EN) COMBINATION TREATMENTS COMPRISING IMIDAZOPYRAZINONES FOR THE TREATMENT OF PSYCHIATRIC AND/OR COGNITIVE DISORDERS
(FR) TRAITEMENTS COMBINÉS COMPRENANT DES IMIDAZOPYRAZINONES POUR LE TRAITEMENT DE TROUBLES PSYCHIATRIQUES ET/OU COGNITIFS
Abstract:
(EN) The present invention provides combination treatments comprising administration of compounds that are PDE1 enzyme inhibitors and other compounds useful in the treatment of psychiatric and/or cognitive disorders such as for example Attention Deficit Hyperactivity Disorder (ADHD), depression, anxiety, narcolepsy, schizophrenia, cognitive impairment or cognitive impairment associated with schizophrenia (CIAS). Separate aspects of the invention are directed to the combined use of said compounds for the treatment of psychiatric and/or cognitive disorders. The present invention also provides pharmaceutical compositions comprising said PDE1 enzyme inhibitors together with other compounds useful in the treatment of psychiatric and/or cognitive disorders.
(FR) La présente invention concerne des traitements combinés comprenant l'administration de composés qui sont des inhibiteurs d'enzyme PDE1 et d'autres composés utiles dans le traitement de troubles psychiatriques et/ou cognitifs tels que, par exemple, le Trouble du Déficit de l'Attention avec Hyperactivité (TDAH), la dépression, l'anxiété, la narcolepsie, la schizophrénie, la déficience cognitive ou la déficience cognitive associée à la schizophrénie (CIAS, pour "Cognitive Impairment Associated with Schizophrenia"). Des aspects séparés de l'invention concernent l'utilisation combinée desdits composés pour le traitement de troubles psychiatriques et/ou cognitifs. La présente invention concerne également des compositions pharmaceutiques comprenant lesdits inhibiteurs d'enzyme PDE1 conjointement avec d'autres composés utiles dans le traitement de troubles psychiatriques et/ou cognitifs.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)