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1. (WO2018078008) INFLUENZA VIRUS NEUTRALIZING COMPOUNDS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/078008 International Application No.: PCT/EP2017/077424
Publication Date: 03.05.2018 International Filing Date: 26.10.2017
IPC:
A61K 38/10 (2006.01) ,A61K 38/12 (2006.01) ,C07K 14/47 (2006.01)
Applicants: JANSSEN VACCINES & PREVENTION B.V.[NL/NL]; Archimedesweg 4 2333 CN Leiden, NL
Inventors: JURASZEK, Jaroslaw; NL
VAN DONGEN, Maria; NL
BRANDENBURG, Boerries; NL
Agent: MANTEN, Annemieke; NL
VERHAGE, Richard, A; NL
BESLIER, Victor; NL
Priority Data:
16195971.327.10.2016EP
Title (EN) INFLUENZA VIRUS NEUTRALIZING COMPOUNDS
(FR) COMPOSÉS DE NEUTRALISATION DE VIRUS DE LA GRIPPE
Abstract:
(EN) The present invention relates to novel compounds, in particular peptidic macrocyclic peptides, that are capable of binding to and/or neutralizing influenza viruses, in particular influenza A viruses comprising HA of the H1 subtype 1, and to pharmaceutical compositions comprising such compounds. The invention also relates to the use of the peptidomimetic 5 compounds in the diagnosis, prophylaxis and/or treatment of influenza virus infections.
(FR) L'invention concerne de nouveaux composés, en particulier des peptides macrocycliques peptidiques, qui peuvent se lier à et/ou neutraliser des virus de la grippe, en particulier les virus de la grippe A, dont HA du sous-type H1, et des compositions pharmaceutiques comprenant ces composés. L'invention concerne également l'utilisation des composés peptidomimétiques dans le diagnostic, la prophylaxie et/ou le traitement d'infections par le virus de la grippe.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)