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1. (WO2018077630) 6,7,8,9-TETRAHYDRO-3H-PYRAZOLO[4,3-F]ISOQUINOLINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER

Pub. No.:    WO/2018/077630    International Application No.:    PCT/EP2017/076191
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Sat Oct 14 01:59:59 CEST 2017
IPC: C07D 471/04
A61K 31/4738
A61K 31/497
A61P 35/00
Applicants: ASTRAZENECA AB
Inventors: SCOTT, James, Stewart
BARLAAM, Bernard, Christophe
YANG, Bin
MOSS, Thomas, Andrew
HUGHES, Samantha, Jayne
NISSINK, Johannes, Wilhelmus, Maria
O'DONOVAN, Daniel, Hillebrand
Title: 6,7,8,9-TETRAHYDRO-3H-PYRAZOLO[4,3-F]ISOQUINOLINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER
Abstract:
The specification relates to compounds of Formula (I) and to pharmaceutically acceptable salts thereof, to processes and intermediates used for their preparation, to pharmaceutical compositions containing them and to their use in the treatment of cell proliferative disorders.