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1. (WO2018077385) DOSE DETERMINATION FOR IMMUNOTHERAPEUTIC AGENTS

Pub. No.:    WO/2018/077385    International Application No.:    PCT/EP2016/075647
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Wed Oct 26 01:59:59 CEST 2016
IPC: G01N 33/50
Applicants: BIONTECH RNA PHARMACEUTICALS GMBH
Inventors: SAHIN, Ugur
JAHNDEL, Veronika
SCHWARCK-KOKARAKIS, Doreen
HÜSEMANN, Yves
DORER, Kathrin
JABULOWSKY, Robert
Title: DOSE DETERMINATION FOR IMMUNOTHERAPEUTIC AGENTS
Abstract:
The present invention relates to methods for determining suitable doses for immunotlierapeutic compounds, whose effectiveness and toxicity can vary at the same dose between individuals due to natural variations within individual subjects, such as variations in the reaction of the immune system in response to administration of such immunotlierapeutic compounds.