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1. (WO2018077187) NOVEL AP26113 CRYSTALS AND PREPARATION METHOD THEREFOR

Pub. No.:    WO/2018/077187    International Application No.:    PCT/CN2017/107652
Publication Date: Fri May 04 01:59:59 CEST 2018 International Filing Date: Thu Oct 26 01:59:59 CEST 2017
IPC: C07D 401/12
A61K 31/506
A61P 35/00
Applicants: CRYSTAL PHARMATECH CO., LTD.
苏州晶云药物科技股份有限公司
Inventors: CHEN, Minhua
陈敏华
ZHANG, Yanfeng
张炎锋
WANG, Jinqiu
王金秋
LIU, Kai
刘凯
ZHANG, Xiaoyu
张晓宇
Title: NOVEL AP26113 CRYSTALS AND PREPARATION METHOD THEREFOR
Abstract:
The present invention relates to two AP26113 crystals and a preparation method therefor. Provided in the present invention, crystal CS1 and crystal CS2 of AP26113 have advantages in terms of solubility and stability, are suitable for process development, provide improved options for preparing a pharmaceutical preparation containing AP26113, and are of great significance to the development of a medicament.