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1. (WO2018076049) IMMUNOGENIC PROTEIN AND METHOD OF USE
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Pub. No.: WO/2018/076049 International Application No.: PCT/AU2017/051164
Publication Date: 03.05.2018 International Filing Date: 24.10.2017
IPC:
A61K 39/108 (2006.01) ,C07K 14/245 (2006.01) ,C12N 15/31 (2006.01) ,C12Q 1/10 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
02
Bacterial antigens
108
Escherichia; Klebsiella
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
24
from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
245
Escherichia (G)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
31
Genes encoding microbial proteins, e.g. enterotoxins
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
02
involving viable micro-organisms
04
Determining presence or kind of micro-organism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
10
Enterobacteria
Applicants:
THE UNIVERSITY OF QUEENSLAND [AU/AU]; St Lucia Brisbane, Queensland 4072, AU
Inventors:
SCHEMBRI, Mark; AU
MORIEL, Danilo; AU
Agent:
SPRUSON & FERGUSON; GPO Box 3898 Sydney, NSW 2001, AU
Priority Data:
201690431424.10.2016AU
Title (EN) IMMUNOGENIC PROTEIN AND METHOD OF USE
(FR) PROTÉINE IMMUNOGÈNE ET MÉTHODE D'UTILISATION
Abstract:
(EN) A method of eliciting an immune response in an animal includes administering an isolated protein comprising the amino acid sequence of SEQ ID NO:1; one or more immunogenic fragments, variants and/or derivatives thereof; an isolated nucleic acid encoding said isolated protein, immunogenic fragment, variant and/or derivative; and/or an antibody or antibody fragment that binds said isolated protein, immunogenic fragment, variant and/or derivative. This may immunize the animal against an E. coli infection and/or treat an existing E. coli infection.
(FR) L'invention concerne une méthode de déclenchement d'une réponse immunitaire chez un animal, comprenant l'administration d'une protéine isolée comprenant la séquence d'acides aminés de SEQ ID NO : 1; un ou plusieurs fragments immunogènes, variants et/ou dérivés de cette dernière; un acide nucléique isolé codant pour ladite protéine isolée, le fragment immunogène, le variant et/ou le dérivé; et/ou un anticorps ou fragment d'anticorps qui se lie à ladite protéine isolée, au fragment immunogène, au variant et/ou au dérivé. Ceci peut immuniser l'animal contre une infection à E. coli et/ou traiter une infection à E. coli existante.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)