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1. (WO2018074327) MUCOSAL IMMUNOMODULATOR
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Pub. No.: WO/2018/074327 International Application No.: PCT/JP2017/037056
Publication Date: 26.04.2018 International Filing Date: 12.10.2017
IPC:
A61K 31/191 (2006.01) ,A23L 33/12 (2016.01) ,A61K 31/194 (2006.01) ,A61K 31/231 (2006.01) ,A61K 39/39 (2006.01) ,A61P 37/02 (2006.01) ,A61P 37/04 (2006.01) ,A61P 37/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
191
Acyclic acids having two or more hydroxy groups, e.g. gluconic acid
[IPC code unknown for A23L 33/12]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
194
having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
22
of acyclic acids, e.g. pravastatin
23
of acids having a carboxyl group bound to a chain of seven or more carbon atoms
231
having one or two double bonds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
39
characterised by the immunostimulating additives, e.g. chemical adjuvants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
02
Immunomodulators
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
02
Immunomodulators
04
Immunostimulants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
02
Immunomodulators
06
Immunosuppressants, e.g. drugs for graft rejection
Applicants:
株式会社山田養蜂場本社 YAMADA BEE COMPANY, INC. [JP/JP]; 岡山県苫田郡鏡野町市場194 194 Ichiba, Kagamino-cho, Tomata-gun, Okayama 7080393, JP
国立大学法人 熊本大学 NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY [JP/JP]; 熊本県熊本市中央区黒髪二丁目39番1号 39-1, Kurokami 2-chome, Chuo-ku, Kumamoto-shi, Kumamoto 8608555, JP
Inventors:
三隅 将吾 MISUMI Shogo; JP
生田 智樹 IKUTA Tomoki; JP
立藤 智基 TATEFUJI Tomoki; JP
谷 央子 TANI Hiroko; JP
井ノ岡 博 INOOKA Hiroshi; JP
Agent:
長谷川 芳樹 HASEGAWA Yoshiki; JP
清水 義憲 SHIMIZU Yoshinori; JP
Priority Data:
2016-20613420.10.2016JP
Title (EN) MUCOSAL IMMUNOMODULATOR
(FR) IMMUNOMODULATEUR MUQUEUX
(JA) 粘膜免疫調節剤
Abstract:
(EN) The present invention provides a mucosal immunomodulator which contains, as an active ingredient, at least one compound selected from the group consisting of a compound represented by general formula (1), a compound represented by general formula (2), a compound represented by general formula (3) and salts of the compounds.
(FR) La présente invention concerne un immunomodulateur muqueux qui contient, à titre de principe actif, au moins un composé choisi dans le groupe constitué par un composé représenté par la formule générale (1), un composé représenté par la formule générale (2), un composé représenté par la formule générale (3) et les sels desdits composés.
(JA) 本発明は、下記一般式(1)で表される化合物、下記一般式(2)で表される化合物、及び下記一般式(3)で表される化合物、並びにこれらの塩からなる群より選択される少なくとも1種を有効成分として含有する、粘膜免疫調節剤を提供する。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)