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1. (WO2018067847) STRUCTURE OF GII.4 NOROVIRUS PROTEASE -DESIGN OF BROAD-SPECTRUM PROTEASE INHIBITORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/067847    International Application No.:    PCT/US2017/055387
Publication Date: 12.04.2018 International Filing Date: 05.10.2017
IPC:
A01N 43/06 (2006.01), A01N 43/50 (2006.01), A01N 43/78 (2006.01), A61K 31/343 (2006.01), A61K 31/381 (2006.01), A61K 31/403 (2006.01)
Applicants: BAYLOR COLLEGE OF MEDICINE [US/US]; One Baylor Plaza Houston, TX 77030-3411 (US)
Inventors: PRASAD, B.v. V, Enkataram; (US).
ESTES, Mary, K.; (US).
SONG, Youngcheng; (US)
Agent: SISTRUNK, Melissa, L.; (US).
SHISHIMA, Gina; (US).
SMITH, Darren; (US)
Priority Data:
62/404,332 05.10.2016 US
Title (EN) STRUCTURE OF GII.4 NOROVIRUS PROTEASE -DESIGN OF BROAD-SPECTRUM PROTEASE INHIBITORS
(FR) STRUCTURE DE DÉFINITION DE PROTÉASE DU NOROVIRUS GII.4 D'INHIBITEURS DE PROTÉASE À LARGE SPECTRE
Abstract: front page image
(EN)The present disclosure concerns inhibitors of Norovirus protease that are suitable for use against any genotype of Norovirus, including at least GII.4 Norovirus proteases. In particular embodiments, specific compositions are encompassed, including their use for prevention or treatment of Norovirus infection in an individual.
(FR)L'invention concerne des inhibiteurs de protéase de norovirus, d'utilisation appropriée contre un quelconque génotype du norovirus, y compris au moins les protéases du norovirus GII.4. Dans des modes de réalisation particuliers, l'invention concerne des compositions spécifiques, y compris leur utilisation pour la prévention ou le traitement d'une infection à norovirus chez un individu.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)