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1. (WO2018067596) KLEBSIELLA PNEUMONIAE CAPSULE POLYSACCHARIDE VACCINES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/067596 International Application No.: PCT/US2017/054978
Publication Date: 12.04.2018 International Filing Date: 03.10.2017
IPC:
A61K 39/108 (2006.01) ,A61K 39/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
02
Bacterial antigens
108
Escherichia; Klebsiella
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
Applicants: DCB-USA LLC[US/US]; 9th Floor, New Castle County 1007 North Orange Street Wilmington, Delaware 19801, US
NATIONAL TAIWAN UNIVERSITY; No.1, Sec.4, Roosevelt Road Taipei, 10617, TW
Inventors: WANG, Jin-Town; TW
WU, Shih-Hsiung; TW
WU, Chung-Yi; TW
Agent: NORTON, Vicki; US
Priority Data:
62/403,36503.10.2016US
62/413,26926.10.2016US
Title (EN) KLEBSIELLA PNEUMONIAE CAPSULE POLYSACCHARIDE VACCINES
(FR) VACCINS À BASE DE POLYSACCHARIDE CAPSULAIRE DE KLEBSIELLA PNEUMONIAE
Abstract:
(EN) The invention provides various immunogens comprising a repeat unit of saccharide of Klebsiella pneumoniae CPS, which has a formula selected from the group consisting of Formulae (I) to (VI) as described herein. Also provided are vaccines comprising one or more immunogens selected from Formula (I) to (VI) and methods of eliciting an immune response against a Klebsiella pneumoniae and preventing infection of Klebsiella pneumoniae by using an immunogen of the invention.
(FR) L'invention concerne divers immunogènes comprenant une unité répétée de saccharide de CPS de Klebsiella pneumoniae qui a une formule sélectionnée dans le groupe constitué par les formules (I) à (VI) telles que décrites dans la description. L'invention concerne également des vaccins comprenant un ou plusieurs immunogènes sélectionnés parmi les formules (I) à (VI), ainsi que des méthodes permettant de déclencher une réponse immunitaire contre Klebsiella pneumoniae et de prévenir une infection à Klebsiella pneumoniae à l'aide d'un immunogène de l'invention.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)