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1. (WO2018067477) METHODS AND REAGENTS TO TREAT AUTOIMMUNE DISEASES AND ALLERGY

Pub. No.:    WO/2018/067477    International Application No.:    PCT/US2017/054805
Publication Date: Fri Apr 13 01:59:59 CEST 2018 International Filing Date: Wed Oct 04 01:59:59 CEST 2017
IPC: A61K 35/17
A61K 31/436
A61K 9/70
A61P 37/06
A61F 13/02
Applicants: WANG, Tian Xin
Inventors: WANG, Tian Xin
Title: METHODS AND REAGENTS TO TREAT AUTOIMMUNE DISEASES AND ALLERGY
Abstract:
The present invention provides compositions for inducing immune tolerance and methods to modify antigen to treat disease such as autoimmune diseases and allergy. Disclosed are compositions, and related methods, comprising APC presentable antigens and immunosuppressants that provide tolerogenic immune responses specific to antigen. In some embodiments, the composition is used for transdermal delivery.