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1. (WO2018067291) IDENTIFICATION AND GENERATION OF PERSONALIZED VACCINE COMPONENTS BY FUNCTIONAL SCREENING VARIABLE EPITOPE AND MIMOTOPE LIBRARIES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/067291    International Application No.:    PCT/US2017/051845
Publication Date: 12.04.2018 International Filing Date: 15.09.2017
IPC:
A61K 39/00 (2006.01), C40B 30/06 (2006.01), C40B 40/10 (2006.01), C07K 4/00 (2006.01), C07K 7/00 (2006.01), C12N 5/0783 (2010.01)
Applicants: PRIMEX CLINICAL LABORATORIES [US/US]; 16742 Stagg St. Suite #120 Van Nuys, CA 91406 (US)
Inventors: MANUCHARYAN, Karen; (MX)
Agent: MURPHY, Timothy, M.; (US).
PETUCHOWSKI, Samuel, J.; (US).
KLAYMAN, Jeffrey, T.; (US).
SUNSTEIN, Bruce, D.; (US).
ASHER, Robert, M.; (US)
Priority Data:
62/395,067 15.09.2016 US
Title (EN) IDENTIFICATION AND GENERATION OF PERSONALIZED VACCINE COMPONENTS BY FUNCTIONAL SCREENING VARIABLE EPITOPE AND MIMOTOPE LIBRARIES
(FR) IDENTIFICATION ET PRODUCTION DE COMPOSANTS VACCINAUX PERSONNALISÉS PAR CRIBLAGE FONCTIONNEL DE BANQUES D'ÉPITOPES ET DE MIMOTOPES VARIABLES
Abstract: front page image
(EN)Specifically, methods for patient stratification and selection of personalized peptide based treatments and vaccines are disclosed, including assays for identifying antigenic and immunogenic peptides involved in immune responses of mammals against pathogens, cancer and other diseases by interrogating the T lymphocyte repertoire of a patient using combinatorial T-cell epitope and mimotope libraries.
(FR)Plus spécifiquement, l'invention concerne des procédés de stratification de patients et de sélection de traitements et de vaccins à base de peptides personnalisés, comprenant des tests permettant d'identifier des peptides antigéniques et immunogènes impliqués dans des réponses immunitaires de mammifères contre des pathogènes, le cancer et d'autres maladies par interrogation du répertoire des lymphocytes T d'un patient en utilisant des banques d'épitopes et de mimotopes de lymphocytes T combinatoires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)