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1. (WO2018067198) INHIBITORY ANTIBODIES AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/067198    International Application No.:    PCT/US2017/022341
Publication Date: 12.04.2018 International Filing Date: 14.03.2017
IPC:
C07K 16/00 (2006.01), C07K 16/46 (2006.01), A61K 39/395 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street, Twelfth Floor Oakland, California 94607-5200 (US)
Inventors: GE, Xin; (US).
NAM, Dong Hyun; (US).
LOPEZ, Tyler; (US)
Agent: KRUEGER, Katherine, A.D.; (US).
VIKSNINS, Ann, S.; (US).
HARRIS, Robert, J.; (US).
MALEN, Peter, L.; (US).
MICKELSON, John, W.; (US).
KLIMA SLIBERG, Catherine., I.; (US).
PADYS, Danny, J.; (US).
LI, Yang; (US)
Priority Data:
62/403,589 03.10.2016 US
Title (EN) INHIBITORY ANTIBODIES AND METHODS OF USE THEREOF
(FR) ANTICORPS INHIBITEURS ET LEURS PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)Certain embodiments of the invention provide an antibody, or a fragment thereof, comprising a heavy chain complementarity-determining region 3 (CDR-H3) having at least about 80% sequence identity to a sequence described herein, as well as methods of use thereof.
(FR)Certains modes de réalisation de l'invention concernent un anticorps, ou un fragment de celui-ci, comprenant une région 3 déterminant la complémentarité de chaîne lourde (CDR-H3) ayant au moins environ 80 % d'identité de séquence par rapport à une séquence décrite dans la description, ainsi que des procédés d'utilisation de ceux-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)