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1. (WO2018066620) PANCREATIC CANCER EVALUATION METHOD, EVALUATION DEVICE, EVALUATION PROGRAM, EVALUATION SYSTEM, AND TERMINAL DEVICE
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Pub. No.: WO/2018/066620 International Application No.: PCT/JP2017/036198
Publication Date: 12.04.2018 International Filing Date: 04.10.2017
IPC:
G01N 33/68 (2006.01) ,G01N 33/48 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
Applicants:
味の素株式会社 AJINOMOTO CO., INC. [JP/JP]; 東京都中央区京橋一丁目15番1号 15-1, Kyobashi 1-chome, Chuo-ku, Tokyo 1048315, JP
Inventors:
中村 英寛 NAKAMURA, Hidehiro; JP
西方 菜摘 NISHIKATA, Natsumi; JP
今泉 明 IMAIZUMI, Akira; JP
新保 和高 SHIMBO, Kazutaka; JP
嵐田 直子 ARASHIDA, Naoko; JP
西本 瑠美 NISHIMOTO, Rumi; JP
Agent:
特許業務法人酒井国際特許事務所 SAKAI INTERNATIONAL PATENT OFFICE; 東京都千代田区霞が関3丁目8番1号 虎の門三井ビルディング Toranomon Mitsui Building, 8-1, Kasumigaseki 3-chome, Chiyoda-ku, Tokyo 1000013, JP
Priority Data:
2016-19671104.10.2016JP
Title (EN) PANCREATIC CANCER EVALUATION METHOD, EVALUATION DEVICE, EVALUATION PROGRAM, EVALUATION SYSTEM, AND TERMINAL DEVICE
(FR) PROCÉDÉ D'ÉVALUATION DE CANCER DU PANCRÉAS, DISPOSITIF D'ÉVALUATION, PROGRAMME D'ÉVALUATION, SYSTÈME D'ÉVALUATION ET DISPOSITIF TERMINAL
(JA) 膵臓癌の評価方法、評価装置、評価プログラム、評価システム、及び端末装置
Abstract:
(EN) The purpose of the present invention is to provide an evaluation method and the like with which it is possible to provide highly reliable information that can serve as a reference for learning the status of pancreatic cancer. According to the present embodiment, the status of pancreatic cancer in an evaluation subject is evaluated using, in blood from the evaluation subject, at least one concentration value among N-Me-bABA, bABA, GABA, N6-Acetyl-L-Lys, 1-Me-His, aABA, Aminoadipic acid, bAiBA, Cadaverine, Ethylglycine, Homoarginine, Hypotaurine, Kinurenine, Putrescine, Serotonin, Spermidine, Spermine, ADMA, Homocitrulline, 3-Me-His, Hydroxyproline, Phosphoethanolamine, Acylcarnitine (13:1), and EPA.
(FR) Le but de la présente invention est de fournir un procédé d'évaluation et similaire avec lequel il est possible de fournir des informations hautement fiables permettant de servir de référence pour l'apprentissage de l'état du cancer du pancréas. Selon le présent mode de réalisation, l'état du cancer du pancréas chez un sujet d'évaluation est évalué en utilisant, dans le sang provenant du sujet d'évaluation, au moins une valeur de concentration parmi N-Me-bABA, bABA, GABA, N6-Acétyl-L-Lys, 1-Me-His, aABA, acide Aminoadipique, bAiBA, Cadavérine, Éthylglycine, Homoarginine, Hypotaurine, Kinurénine, Putrescine, Sérotonine, Spermidine, Spermine, ADMA, Homocitrulline, 3-Me-His, Hydroxyproline, Phosphoéthanolamine, Acylcarnitine (13:1) et EPA.
(JA) 膵臓癌の状態を知る上で参考となり得る信頼性の高い情報を提供することができる評価方法などを提供することを課題とする。本実施形態では、評価対象の血液中のN-Me-bABA,bABA,GABA,N6-Acetyl-L-Lys,1-Me-His,aABA,Aminoadipic acid,bAiBA,Cadaverine,Ethylglycine,Homoarginine,Hypotaurine,Kinurenine,Putrescine,Serotonin,Spermidine,Spermine,ADMA,Homocitrulline,3-Me-His,Hydroxyproline,Phosphoethanolamine,Acylcarnitine(13:1),EPAのうちの少なくとも1つの濃度値を用いて、評価対象について、膵臓癌の状態を評価する。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)