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1. (WO2018066595) COLLAGEN COMPOSITION

Pub. No.:    WO/2018/066595    International Application No.:    PCT/JP2017/036110
Publication Date: Fri Apr 13 01:59:59 CEST 2018 International Filing Date: Thu Oct 05 01:59:59 CEST 2017
IPC: C07K 14/78
C07K 1/12
C07K 1/14
C07K 1/34
Applicants: KINDAI UNIVERSITY
学校法人近畿大学
UHA MIKAKUTO CO., LTD.
ユーハ味覚糖株式会社
Inventors: TAGA Atsushi
多賀 淳
YAMAMOTO Tetsushi
山本 哲志
KASHIMA Yasuhiro
鹿島 康浩
DOI Satoshi
土井 聡
MATSUKAWA Taiji
松川 泰治
YAMADA Yasumasa
山田 泰正
YAMADA Ichiro
山田 一郎
Title: COLLAGEN COMPOSITION
Abstract:
A collagen composition in which the content of collagens each having a molecular weight of 90,000 or higher is 70% or higher on a solid basis with respect to the mass of the proteins, and which has a solubility in water (25°C) of 10% or higher and, in an examination by electrophoresis under non-reducing non-heating conditions, shows bands indicating an α chain, a β chain, and a γ chain. The collagen composition can be produced by: either treating a fish skin with a strong-acid dilution and then with a strong-alkali dilution or treating a fish skin with a strong-alkali dilution and then with a strong-acid dilution; extracting collagens from the resultant fish skin with a dilute weak-acid solution; and purifying the extracted collagens by ultrafiltration or equilibrium dialysis.