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1. (WO2018065525) CLASSIFICATION AND PROGNOSIS OF CANCER
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/065525    International Application No.:    PCT/EP2017/075368
Publication Date: 12.04.2018 International Filing Date: 05.10.2017
IPC:
C12Q 1/68
Applicants: UNIVERSITY OF EAST ANGLIA [GB/GB]; Norwich Norfolk NR4 7TJ (GB)
Inventors: LUCA, Bogdan-Alexandru; (GB).
MOULTION, Vincent; (GB).
BREWER, Daniel Simon; (GB).
COOPER, Colin Stephen; (GB)
Agent: LEONARD, Thomas; (GB)
Priority Data:
1616912.0 05.10.2016 GB
Title (EN) CLASSIFICATION AND PROGNOSIS OF CANCER
(FR) CLASSIFICATION ET PRONOSTIC DE CANCER
Abstract: front page image
(EN)The present invention relates to the classification of cancers, in particular prostate cancers, using samples from patients. In particular, the invention provides methods for identifying potentially aggressive prostate cancers to determine which cancers are or will become aggressive (and hence require treatment) and which will remain indolent (and will therefore not require treatment). The present invention is therefore useful to identify patients with a poor prognosis. The specific population of cancer identified by the present invention is referred to herein as DESNT cancer. The invention also provides biomarker panels useful in the diagnosis and prognosis of cancer.
(FR)La présente invention concerne la classification de cancers, en particulier de cancers de la prostate, à l'aide d'échantillons provenant de patients. En particulier, l'invention concerne des procédés d'identification de cancers de la prostate potentiellement agressifs pour déterminer les cancers qui sont ou qui deviendront agressifs (et nécessitent donc un traitement) et ceux qui resteront de faible malignité (et ne nécessiteront donc pas de traitement). La présente invention est donc utile pour identifier des patients présentant un pronostic défavorable. La population spécifique de cancer identifiée par la présente invention est désignée dans la description comme un cancer DESNT. L'invention concerne également des panels de biomarqueurs utiles dans le diagnostic et le pronostic du cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)