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1. (WO2018065446) [6R]-MTHF - AN EFFICIENT FOLATE ALTERNATIVE IN 5-FLUOROURACIL BASED CHEMOTHERAPY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/065446    International Application No.:    PCT/EP2017/075155
Publication Date: 12.04.2018 International Filing Date: 04.10.2017
IPC:
A61K 39/00 (2006.01), A61K 31/4745 (2006.01), A61K 31/513 (2006.01), A61K 31/519 (2006.01), A61P 35/00 (2006.01)
Applicants: ISOFOL MEDICAL AB [SE/SE]; Biotech center Arvid Wallgrens Backe 20 416 46 Göteborg (SE)
Inventors: LINDBERG, Per Lennart; (SE).
SUNDÉN, Gunnel Elisabeth; (SE).
GUSTAVSSON, Bengt; (SE).
VEDIN, Anders; (SE)
Agent: AWAPATENT A/S; Strandgade 56 Denmark 1401 Copenhagen K (DK)
Priority Data:
16192366.9 05.10.2016 EP
17187684.0 24.08.2017 EP
Title (EN) [6R]-MTHF - AN EFFICIENT FOLATE ALTERNATIVE IN 5-FLUOROURACIL BASED CHEMOTHERAPY
(FR) [6R]-MTHF - ALTERNATIVE EFFICACE DU FOLATE DANS LA CHIMIOTHÉRAPIE À BASE DE 5-FLUOROURACILE
Abstract: front page image
(EN)The present invention relates to the treatment of solid tumors in humans such as cancer, especially colorectal cancer (CRC), which involves administering the diastereomerically pure folate adjuvant [6R]-5,10-methylenetetrahydrofolate in 5-fluorouracil (5-FU) based chemotherapy.
(FR)La présente invention concerne le traitement de tumeurs solides chez des êtres humains tels que le cancer, en particulier le cancer colorectal (CRC), qui consiste à administrer l'adjuvant de folate diastéréomériquement pur [6R] -5,10-méthylènetétrahydrofolate dans une chimiothérapie à base de 5-fluorouracile (5-FU) .
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)