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1. (WO2018064470) METHODS OF DIAGNOSING AND TREATING ABIRATERONE ACETATE- GLUCOCORTICOID -RESISTANT OR -SENSITIVE METASTATIC CASTRATION RESISTANT PROSTATE CANCER
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Pub. No.:    WO/2018/064470    International Application No.:    PCT/US2017/054286
Publication Date: 05.04.2018 International Filing Date: 29.09.2017
IPC:
C12Q 1/68
Applicants: JANSSEN PHARMACEUTICA NV [BE/BE]; Turnhoutseweg 30 2340 Beerse (BE).
LI, Weimin [US/US]; (US) (US only)
Inventors: LI, Weimin; (US).
KAWAGUCHI, Kazushiro; (JP).
OYAMA, Ryo; (JP).
PATEL, Jaymala; (US).
SMIRNOV, Denis; (US)
Agent: SHIRTZ, Joseph F.; (US).
TRACY, Timothy E.; (US)
Priority Data:
62/402,196 30.09.2016 US
Title (EN) METHODS OF DIAGNOSING AND TREATING ABIRATERONE ACETATE- GLUCOCORTICOID -RESISTANT OR -SENSITIVE METASTATIC CASTRATION RESISTANT PROSTATE CANCER
(FR) MÉTHODES DE DIAGNOSTIC ET DE TRAITEMENT DU CANCER DE LA PROSTATE MÉTASTATIQUE RÉSISTANT À LA CASTRATION SENSIBLE OU RÉSISTANT À L'ACÉTATE D'ABIRATÉRONE-GLUCOCORTICOIDES
Abstract: front page image
(EN)Disclosed herein are novel biomarkers for detecting resistance and sensitivity to abiraterone acetate-glucocorticoid treatment in a patient having metastatic castration resistant prostate cancer. Also provided are methods of diagnosing and treating abiraterone acetate-glucocorticoid resistant and abiraterone acetate-glucocorticoid sensitive metastatic castration resistant prostate cancer.
(FR)L'invention concerne de nouveaux biomarqueurs pour la détection de la résistance et de la sensibilité à un traitement d'acétate d'abiratérone-glucocorticoïdes chez un patient ayant un cancer de la prostate métastatique résistant à la castration. L'invention concerne également des méthodes de diagnostic et de traitement d'un cancer de la prostate métastatique résistant à la castration sensible à l'acétate d'abiratérone-glucocorticoïdes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)