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1. (WO2018064255) ANTIBODIES THAT BIND INTERLEUKIN-2 AND USES THEREOF
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Pub. No.: WO/2018/064255 International Application No.: PCT/US2017/053880
Publication Date: 05.04.2018 International Filing Date: 28.09.2017
Chapter 2 Demand Filed: 03.08.2018
IPC:
A61K 39/395 (2006.01) ,C07K 16/24 (2006.01) ,A61K 39/00 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
24
against cytokines, lymphokines or interferons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
XOMA (US) LLC [US/US]; 2910 Seventh Street Berkeley, CA 94710, US
MUSC FOUNDATION FOR RESEARCH DEVELOPMENT [US/US]; 19 Hagood Avenue, Suite 909 Charleston, SC 29425, US
Inventors:
ROELL, Marina; US
RUBINSTEIN, Mark; US
ISSAFRAS, Hassan; US
LAO, Llewelyn; US
LI, Ou; US
BEDINGER, Daniel, H.; US
LIND, Kristin, Camfield; US
HOLMES, Agnes, Choppin; US
TAKEUCHI, Toshihiko; US
SCHWIMMER, Lauren; US
GIANG, Hoa; US
MIRZA, Amer, M.; US
JOHNSON, Kirk, W.; US
Agent:
NEVILLE, Katherine, L.; US
Priority Data:
62/401,15828.09.2016US
62/421,03811.11.2016US
Title (EN) ANTIBODIES THAT BIND INTERLEUKIN-2 AND USES THEREOF
(FR) ANTICORPS SE LIANT À L'INTERLEUKIN-2 ET LEURS UTILISATIONS
Abstract:
(EN) The present disclosure relates, in general, to human antibodies against human interleukin 2 (IL-2) and methods of use of such antibodies for modulating IL-2 activity and use in the treatment of conditions such as cancer, autoimmune disease, or infection.
(FR) La présente invention concerne, en général, des anticorps humains contre l'interleukine 2 humaine (IL -2) et des procédés d'utilisation de ces anticorps pour moduler l'activité de l'IL -2 et leur utilisation dans le traitement d'états tels que le cancer, une maladie auto-immune ou une infection.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)