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1. (WO2018063999) DETECTION OF TARGET ANALYTES AT PICOMOLAR CONCENTRATIONS
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Pub. No.: WO/2018/063999 International Application No.: PCT/US2017/053319
Publication Date: 05.04.2018 International Filing Date: 25.09.2017
IPC:
B03C 1/00 (2006.01) ,B03C 5/02 (2006.01)
B PERFORMING OPERATIONS; TRANSPORTING
03
SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
C
MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
1
Magnetic separation
B PERFORMING OPERATIONS; TRANSPORTING
03
SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
C
MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
5
Separating dispersed particles from liquids by electrostatic effect
02
Separators
Applicants:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street, 12th Floor Oakland, California 94607-5200, US
Inventors:
YANIK, Ahmet Ali; US
ZHU, Xiangchao; US
Agent:
CHANDRA, Shweta; US
Priority Data:
62/400,30727.09.2016US
Title (EN) DETECTION OF TARGET ANALYTES AT PICOMOLAR CONCENTRATIONS
(FR) DÉTECTION D'ANALYTES CIBLES À DES CONCENTRATIONS PICOMOLAIRES
Abstract:
(EN) Methods for detecting submolar concentrations of a target analyte in a sample are disclosed. These methods combine a process of biomarker to bead conversion with bead enrichment and simple visual, optical, or electrochemical detection of the presence of enriched beads to provide sensitive and inexpensive assay for detecting analytes in a sample. Devices for performing these methods are also disclosed.
(FR) La présente invention concerne des procédés permettant de détecter des concentrations submolaires d'un analyte cible dans un échantillon. Ces procédés combinent un processus de conversion de biomarqueur en perles avec un enrichissement de perles et une simple détection visuelle, optique ou électrochimique de la présence de perles enrichies pour fournir un dosage sensible et peu coûteux pour détecter des analytes dans un échantillon. La présente invention porte également sur des dispositifs permettant de réaliser ces procédés.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)