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1. (WO2018063016) NEW PLATINUM(II) DICARBOXYLATE COMPLEXES WITH 5,7-DISUBSTITUTED-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINE AND DIMETHYL SULFOXIDE, AND THEIR PREPARATION METHOD

Pub. No.:    WO/2018/063016    International Application No.:    PCT/PL2017/050046
Publication Date: Fri Apr 06 01:59:59 CEST 2018 International Filing Date: Mon Sep 18 01:59:59 CEST 2017
IPC: C07F 15/00
A61P 35/00
Applicants: UNIWERSYTET MIKOŁAJA KOPERNIKA W TORUNIU
Inventors: ŁAKOMSKA, Iwona
JAKUBOWSKI, Mateusz
Title: NEW PLATINUM(II) DICARBOXYLATE COMPLEXES WITH 5,7-DISUBSTITUTED-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINE AND DIMETHYL SULFOXIDE, AND THEIR PREPARATION METHOD
Abstract:
The invention relates of new platinum(ll) dicarboxylate complexes with the following formulas: formula 1 [Pt(mal)(dmso)(dptp)] · dmso and formula 2 [Pt(CBDC)(dmso)(dmtp)] · dmso, where: CBDC - cyclobutane-l,l-dicarboxylate, dmso - dimethyl sulfoxide, dmtp - 5,7-dimethyl-l,2,4-triazolo [l,5-a]pyrimidine, dptp - 5,7-diphenyl-l,2,4-triazolo[l,5-a]pyrimidine, mal - malonate. The invention reveals also to method of their preparation.