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1. (WO2018062876) KIT FOR TREATMENT OF OSTEOARTHRITIS TO REDUCE PAIN
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/062876    International Application No.:    PCT/KR2017/010766
Publication Date: 05.04.2018 International Filing Date: 27.09.2017
IPC:
Applicants: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION [KR/KR]; 222, Banpo-daero Seocho-gu Seoul 06591 (KR)
Inventors: CHO, Mi-La; (KR).
KIM, Seok-Jung; (KR).
LEE, Seon-Yeong; (KR).
LEE, Seung-Hoon; (KR).
NA, Hyun-Sik; (KR).
MOON, Su-Jin; (KR).
KWUAN, Ji-Ye; (KR).
JUNG, Kyung-Ah; (KR).
KIM, Eun-Kyung; (KR).
KIM, Seon-Ae; (KR)
Agent: WIE, Byoung-Gap; (KR)
Priority Data:
10-2016-0123831 27.09.2016 KR
Title (EN) KIT FOR TREATMENT OF OSTEOARTHRITIS TO REDUCE PAIN
(FR) KIT POUR LE TRAITEMENT DE L'ARTHROSE VISANT À RÉDUIRE LA DOULEUR
(KO) 통증이 경감되는 골관절염 치료용 키트
Abstract: front page image
(EN)The present invention relates to a kit for treatment of osteoarthritis to reduce pain, the kit comprising: a composition for intravenous administration, comprising STAT3 inhibitor-treated mesenchymal stem cells as an effective ingredient; and a composition for intraarticular administration, comprising mesenchymal stem cells as an effective ingredient, and a method for prevention and treatment of osteoarthritis by using the same. Osteoarthritis can be treated with the reduction of pain thereof by simultaneously administering STAT3 inhibitor-treated mesenchymal stem cells via an intravenous route and mesenchymal stem cells via an intraarticular route.
(FR)La présente invention concerne un kit pour le traitement de l'arthrose visant à réduire la douleur, le kit comprenant : une composition pour administration intraveineuse, comprenant des cellules souches mésenchymateuses traitées par un inhibiteur de STAT3 en tant que principe actif; et une composition pour administration intraarticulaire, comprenant des cellules souches mésenchymateuses en tant que principe actif, et un procédé de prévention et de traitement de l'arthrose les utilisant. L'arthrose peut être traitée avec réduction de la douleur associée par l'administration simultanée de cellules souches mésenchymateuses traitées par un inhibiteur STAT3 par voie intraveineuse et de cellules souches mésenchymateuses par voie intraarticulaire.
(KO)본 발명은 STAT3 억제제가 처리된 간엽줄기세포를 유효성분으로 포함하는 정맥내 투여용 조성물; 및 간엽줄기세포를 유효성분으로 포함하는 관절강내 투여용 조성물을 포함하는 통증이 경감되는 골관절염 치료용 키트 및 이를 이용한 골관절염 예방 및 치료 방법에 관한 것으로, STAT3 억제제가 처리된 간엽줄기세포를 정맥내 투여하고 동시에 간엽줄기세포를 관절강내 투여함으로써 골관절염의 통증을 경감시키면서도 치료할 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)