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1. (WO2018062134) PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/062134 International Application No.: PCT/JP2017/034654
Publication Date: 05.04.2018 International Filing Date: 26.09.2017
IPC:
A61K 31/538 (2006.01) ,A61K 45/06 (2006.01) ,A61P 1/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
535
having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
5375
1,4-Oxazines, e.g. morpholine
538
ortho- or peri-condensed with carbocyclic ring systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
16
for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Applicants: MITSUBISHI TANABE PHARMA CORPORATION[JP/JP]; 3-2-10, Dosho-machi, Chuo-ku, Osaka-shi, Osaka 5418505, JP
Inventors: COOREMAN, Michael P.; US
KIKKAWA, Kohei; JP
Agent: SAMEJIMA, Mutsumi; JP
MORIMOTO, Yasushi; JP
Priority Data:
62/40020027.09.2016US
Title (EN) PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE
(FR) COMPOSITION PHARMACEUTIQUE ET MÉTHODE DE TRAITEMENT D'UNE MALADIE DU FOIE GRAS NON ALCOOLIQUE
Abstract:
(EN) The present invention provides a pharmaceutical composition for prophylaxis and treatment of NAFLD comprising as an active ingredient a 1,4-benzoxazine compound represented by formula (I): or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, as well as a method for prophylaxis and treatment of NAFLD which comprises administering a therapeutically effective amount of the above-mentioned 1,4-benzoxazine compound represented by formula (I) and so on to a patient in need thereof.
(FR) La présente invention concerne une composition pharmaceutique pour la prophylaxie et le traitement de la NASH comprenant, en tant que principe actif, un composé de 1,4-benzoxazine représenté par la formule (I) ou un sel pharmaceutiquement acceptable de celui-ci, et un support pharmaceutiquement acceptable, ainsi qu'une méthode de prophylaxie et de traitement de la NASH qui comprend l'administration d'une quantité thérapeutiquement efficace du composé 1,4-benzoxazine mentionné ci-dessus représenté par la formule (I) etc à un patient qui en a besoin.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)