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1. (WO2018060948) INJECTABLE HYDROGEL-FORMING POLYMER SOLUTION FOR A RELIABLE EEG MONITORING AND EASY SCALP CLEANING
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Pub. No.: WO/2018/060948 International Application No.: PCT/IB2017/056012
Publication Date: 05.04.2018 International Filing Date: 29.09.2017
IPC:
A61B 5/0476 (2006.01) ,C08J 3/075 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
04
Measuring bioelectric signals of the body or parts thereof
0476
Electroencephalography
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
J
WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H142
3
Processes of treating or compounding macromolecular substances
02
Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
03
in aqueous media
075
Macromolecular gels
Applicants:
UNIVERSIDADE DO PORTO [PT/PT]; Reitoria da Universidade do Porto, Praça Gomes Teixeira 4099-002 Porto, PT
TECHNISCHE UNIVERSITAT ILMENAU [DE/DE]; Ehrenbergstraße 29 98693 Ilmenau, DE
Inventors:
MAGALHÃES DUQUE DA FONSECA, José Carlos; PT
TEIXEIRA BATISTA PEDROSA, Paulo Eduardo; PT
FIEDLER, Patrique; DE
OLIVEIRA MARTINS, Ana Cristina; PT
HAUEISEN, Jans; DE
Agent:
PEREIRA DA CRUZ, João; PT
Priority Data:
10964730.09.2016PT
Title (EN) INJECTABLE HYDROGEL-FORMING POLYMER SOLUTION FOR A RELIABLE EEG MONITORING AND EASY SCALP CLEANING
(FR) SOLUTION DE POLYMÈRE INJECTABLE FORMANT UN HYDROGEL POUR UNE SURVEILLANCE D'EEG FIABLE ET UN NETTOYAGE AISÉ DU CUIR CHEVELU
Abstract:
(EN) An injectable composition is described, which is capable of forming an hydrogel for electroencephalography (EEG) recording. The obtained hydrogel and method for its production is also an object of the invention, as well as the use of the injectable composition for EEG recording. The injectable composition comprises: natural or synthetic polymers, preferably alginate; a polymerization initiation system or a cross-linking agent, preferably calcium salts; and at least one ionized salt. The injectable composition can be applied into the electrode cavities of common commercial EEG caps and forms a solid hydrogel shortly after application. When the cap is taken off, the hydrogel either remains inside the electrode cavities, or it breaks into parts that are easily removed from the hair with a comb. It can thus be handled and applied just like any other commercial electrolytic gel, but allows a faster and easier cleaning, it reduces movement artefacts and also the risks of electrodes short-circuiting due to gel running, hence increasing EEG data reliability.
(FR) La présente invention concerne une composition injectable, qui est capable de former un hydrogel pour un enregistrement d'électro-encéphalographie (EEG). L'hydrogel obtenu et son procédé de production sont également un objet de l'invention, ainsi que l'utilisation de la composition injectable pour l'enregistrement d'EEG. La composition injectable comprend : des polymères naturels ou synthétiques, de préférence un alginate; un système d'initiation de polymérisation ou un agent de réticulation, de préférence des sels de calcium; et au moins un sel ionisé. La composition injectable peut être appliquée dans les cavités d'électrode de casques d'EEG commerciaux courants et forme un hydrogel solide peu après l'application. Lorsque le casque est retiré, l'hydrogel reste à l'intérieur des cavités d'électrode, ou il se rompt en morceaux qui sont facilement retirés des cheveux avec un peigne. Il peut ainsi être manipulé et appliqué simplement comme tout autre gel électrolytique commercial, mais permet un nettoyage plus rapide et plus aisé, il réduit les artefacts de mouvement ainsi que les risques de court-circuitage d'électrodes dû à l'écoulement du gel, de façon à augmenter la fiabilité des données EEG.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)