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1. (WO2018060438) METHODS OF TREATING FEMALE INFERTILITY

Pub. No.:    WO/2018/060438    International Application No.:    PCT/EP2017/074800
Publication Date: Fri Apr 06 01:59:59 CEST 2018 International Filing Date: Sat Sep 30 01:59:59 CEST 2017
IPC: A61K 38/08
A61P 5/24
Applicants: MYOVANT SCIENCES GMBH
Inventors: RAJASEKHAR, Vijaykumar Reddy
JOHNSON, Brendan Mark
WILLIAMS, Laura Ann
Title: METHODS OF TREATING FEMALE INFERTILITY
Abstract:
Further according to the present disclosure, there are methods for promoting egg maturation in assisted reproductive technologies, such as in in vitro fertilization (IVF) or in an embryo transfer (ET) process. There are also methods for decreasing the rate of ovarian hyper- stimulation syndrome (OHSS), providing comparable or improved pregnancy rates, decreasing the time to pregnancy, and inhibiting premature ovulation. The methods include the step of administering a therapeutically effective amount of an active pharmaceutical ingredient of 2-(N-acetyl-D-tyrosyl-trans-4-hydroxy-L-prolyl-L-asparaginyl-L-threonyl-L-phenylalanyl) hydrazinocarbonyl-L-leucyl-Nro-methyl-L-arginyl-L-tryptophanamide or a pharmaceutically acceptable salt thereof.