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1. (WO2018060321) COMPOSITION COMPRISING A BIOACTIVE MOLECULE

Pub. No.:    WO/2018/060321    International Application No.:    PCT/EP2017/074606
Publication Date: Fri Apr 06 01:59:59 CEST 2018 International Filing Date: Fri Sep 29 01:59:59 CEST 2017
IPC: A01N 43/90
A01N 43/12
A01N 45/00
A61K 47/18
A61K 47/10
A61K 31/56
A61K 31/7048
Applicants: EUCARYO BEHEER B.V.
Inventors: LITH VAN, Wilhelmus Antonius Maria
Title: COMPOSITION COMPRISING A BIOACTIVE MOLECULE
Abstract:
The invention relates to a process for preparing a composition comprising a bioactive molecule comprising the steps of a. Dissolving a bioactive molecule having at least one acid group with a base at pH=>11 to obtain a solution A b. Neutralizing the solution A with an acid to obtain the composition comprising a bioactive molecule having a pH between 6 and 9, wherein PEG is added before the neutralizing step in case either the base and/or the acid is an inorganic compound, and to a composition comprising a high concentration of natamycin.