Search International and National Patent Collections

1. (WO2018060288) COMPOSITIONS AND METHODS OF TREATMENT OF PERSISTENT HPV INFECTION

Pub. No.:    WO/2018/060288    International Application No.:    PCT/EP2017/074552
Publication Date: Fri Apr 06 01:59:59 CEST 2018 International Filing Date: Thu Sep 28 01:59:59 CEST 2017
IPC: A61K 39/12
C07K 14/005
Applicants: GLAXOSMITHKLINE BIOLOGICALS S.A.
Inventors: BURNY, Wivine
CASTADO, Cindy
GIANNINI, Sandra
MASSAUX, Julien, Thierry
Title: COMPOSITIONS AND METHODS OF TREATMENT OF PERSISTENT HPV INFECTION
Abstract:
The present invention relates to nucleic acid constructs capable of encoding antigenic peptides or polypeptides derived from multiple Human Papilloma Virus (HPV) early proteins, and to immunogenic compositions comprising such nucleic acid constructs and a pharmaceutically acceptable carrier. Such nucleic acid constructs and immunogenic compositions are useful in the treatment of persistent HPV infection and low-grade HPV lesions, particularly infections and lesions of human anogenital epithelial tissue, such as cervical epithelia.