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1. (WO2018060072) NEW SUBSTITUTED BENZIMIDAZOLES, METHODS FOR THE PRODUCTION OF SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAME, AND USE OF SAME TO PRODUCE DRUGS

Pub. No.:    WO/2018/060072    International Application No.:    PCT/EP2017/074016
Publication Date: Fri Apr 06 01:59:59 CEST 2018 International Filing Date: Sat Sep 23 01:59:59 CEST 2017
IPC: C07D 413/14
C07D 409/14
C07D 417/14
A61K 31/4439
Applicants: BAYER PHARMA AKTIENGESELLSCHAFT
Inventors: BOTHE, Ulrich
RING, Sven
NUBBEMEYER, Reinhard
ULF, Bömer
NIEHUES, Michael
SCHMIDT, Nicole
WERBECK, Nicolas
CLEVE, Arwed
SUTTER, Andreas
PETERS, Michaele
LAUX-BIEHLMANN, Alexis
Title: NEW SUBSTITUTED BENZIMIDAZOLES, METHODS FOR THE PRODUCTION OF SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAME, AND USE OF SAME TO PRODUCE DRUGS
Abstract:
The invention relates to new substituted benzimidazoles, to methods for the production thereof, to the use thereof alone or in combinations to treat and/or prevent diseases, and to the use thereof to produce drugs for treating and/or preventing diseases, in particular for treating and/or preventing endometriosis and endometriosis-associated pains and other symptoms associated with endometriosis such as dysmenorrhea, dyspareunia, dysuria, and dyschezia, lymphomas, rheumatoid arthritis, spondyloarthritides (in particular psoriatic spondyloarthritis and Bekhterev's disease), lupus erythematosus, multiple sclerosis, macular degeneration, COPD, gout, fatty liver diseases, insulin resistance, kidney diseases, tumor diseases, and psoriasis.