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1. (WO2018058123) METHODS OF TREATING TIM-3 ELEVATION
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Pub. No.: WO/2018/058123 International Application No.: PCT/US2017/053496
Publication Date: 29.03.2018 International Filing Date: 26.09.2017
IPC:
A61K 39/39 (2006.01) ,A61K 39/395 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
39
characterised by the immunostimulating additives, e.g. chemical adjuvants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
ADVANTAGENE, INC. [US/US]; 440 Lexington Street Auburndale, MA 02466, US
Inventors:
AGUILAR-CORDOVA, Estuardo; US
GUZIK, Brian; US
AGUILAR, Laura, Kaye; US
CHIOCCA, Antonio, E.; US
LAWLER, Sean; US
SPERANZA, Maria, Carmella; US
Agent:
KERNER, Ann-Louise; US
Priority Data:
62/399,97626.09.2016US
Title (EN) METHODS OF TREATING TIM-3 ELEVATION
(FR) PROCÉDÉS DE TRAITEMENT DE LA HAUSSE DU NIVEAU DE TIM-3
Abstract:
(EN) The present disclosure provides formulations and therapies for treating subjects with elevated levels of TIM- 3 using gene -based cytotoxic immunostimulant therapy alone or with other immunotherapies.
(FR) La présente invention concerne des formulations et des thérapies pour traiter des sujets ayant des taux élevés de TIM-3 à l'aide d'une thérapie immunostimulante cytotoxique basée sur un gène seul ou avec d'autres immunothérapies.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)