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1. (WO2018058067) AUTOLOGOUS IRRADIATED WHOLE CELL TUMOR VACCINES LENTIVIRALLY ENGINEERED TO EXPRESS CD80, IL-15 AND IL-15 RECEPTOR ALPHA
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2018/058067    International Application No.:    PCT/US2017/053313
Publication Date: 29.03.2018 International Filing Date: 25.09.2017
IPC:
A61K 38/19 (2006.01), A61K 39/00 (2006.01), C12N 15/864 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street Twelfth Floor Oakland, CA 94607-5200 (US)
Inventors: GAENSLER, Karin; (US)
Agent: SHOW, Matthew, D.; (US).
AMENDT, Kevin, C.; (US).
ADAMS, Lisa; (US).
AZRIN, Linda, B.; (US).
BAUER, John, A.; (US)
Priority Data:
62/398,980 23.09.2016 US
Title (EN) AUTOLOGOUS IRRADIATED WHOLE CELL TUMOR VACCINES LENTIVIRALLY ENGINEERED TO EXPRESS CD80, IL-15 AND IL-15 RECEPTOR ALPHA
(FR) VACCINS ANTITUMORAUX À CELLULES ENTIÈRES IRRADIÉS AUTOLOGUES, MODIFIÉS PAR VOIE LENTIVIRALE POUR EXPRIMER CD80, IL-15 ET LE RÉCEPTEUR ALPHA D'IL-15
Abstract: front page image
(EN)Provided herein, inter alia, are cell media compositions and whole cell vaccines comprising recombinant cells expressing IL-15, IL-15Rα, and CD80 capable of treating and preventing relapse in individuals diagnosed with or thought to have leukemia as well as methods for using the same.
(FR)L'invention concerne, entre autres, des compositions de milieux celluaires et de vaccins à cellules entières comprenant des cellules recombinées exprimant IL-15, IL-15Rα et CD80, aptes à traiter ou prévenir une rechute pour des individus chez lesquels une leucémie est diagnostiquée ou suspectée, ainsi que des méthodes d'utilisation associées.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)